[HTML][HTML] Enzyme immobilization strategies for the design of robust and efficient biocatalysts
JM Guisan, G Fernandez-Lorente… - Current Opinion in …, 2022 - Elsevier
Different strategies for the preparation of efficient and robust immobilized biocatalysts are
here reviewed. Different physico-chemical approaches are discussed. i.-The stabilization of …
here reviewed. Different physico-chemical approaches are discussed. i.-The stabilization of …
Iron insertion into coproporphyrin III‐ferrochelatase complex: Evidence for an intermediate distorted catalytic species
Understanding the reaction mechanism of enzymes at the molecular level is generally a
difficult task, since many parameters affect the turnover. Often, due to high reactivity and …
difficult task, since many parameters affect the turnover. Often, due to high reactivity and …
Development of a growth-coupled selection platform for directed evolution of heme biosynthetic enzymes in Corynebacterium glutamicum
Y Zhou, J Chen, W Pu, N Cai, B Che, J Yang… - … in Bioengineering and …, 2023 - frontiersin.org
Heme is an important tetrapyrrole compound, and has been widely applied in food and
medicine industries. Although microbial production of heme has been developed with …
medicine industries. Although microbial production of heme has been developed with …
Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation
A Dali, T Gabler, F Sebastiani, A Destinger… - Protein …, 2023 - Wiley Online Library
Coproporphyrin ferrochelatases (CpfCs) are enzymes catalyzing the penultimate step in the
coproporphyrin‐dependent (CPD) heme biosynthesis pathway, which is mainly utilized by …
coproporphyrin‐dependent (CPD) heme biosynthesis pathway, which is mainly utilized by …
Bacteroides fragilis expresses three proteins similar to Porphyromonas gingivalis HmuY: Hemophore‐like proteins differentially evolved to participate in heme …
SV Antonyuk, K Siemińska, M Śmiga… - The FASEB …, 2023 - Wiley Online Library
Oral and gut microbiomes are important for the maintenance of homeostasis in the human
body. Altered or disturbed mutualism between their members results in dysbiosis with local …
body. Altered or disturbed mutualism between their members results in dysbiosis with local …
The combination of resonance Raman spectroscopy and site directed mutagenesis to study the diverse aspects of heme protein structure and function
This review provides examples illustrating the powerful combination of resonance Raman
spectroscopy and site-directed mutagenesis to investigate the structure-function relationship …
spectroscopy and site-directed mutagenesis to investigate the structure-function relationship …
The Role of the Hydrogen Bond Network in Maintaining Heme Pocket Stability and Protein Function Specificity of C. diphtheriae Coproheme Decarboxylase
Monoderm bacteria accumulate heme b via the coproporphyrin-dependent biosynthesis
pathway. In the final step, in the presence of two molecules of H2O2, the propionate groups …
pathway. In the final step, in the presence of two molecules of H2O2, the propionate groups …
[HTML][HTML] Comparative efficacy of essential oils against Cutibacterium acnes: Effect upon strains from phylotypes with different virulence patterns
AS Oliveira, C Gaspar, J Rolo… - Microbial …, 2025 - Elsevier
Objectives Despite being a commensal of human skin, Cutibacterium acnes plays an
important role in the pathogenesis of Acne vulgaris, with the loss of bacterial phylotype …
important role in the pathogenesis of Acne vulgaris, with the loss of bacterial phylotype …
[HTML][HTML] Nitrobindin versus myoglobin: A comparative structural and functional study
G De Simone, A di Masi, A Pasquadibisceglie… - Journal of Inorganic …, 2024 - Elsevier
Most hemoproteins display an all-α-helical fold, showing the classical three on three (3/3)
globin structural arrangement characterized by seven or eight α-helical segments that form a …
globin structural arrangement characterized by seven or eight α-helical segments that form a …
Revisiting catalytic His and Glu residues in coproporphyrin ferrochelatase–unexpected activities of active site variants
T Gabler, A Dali, M Bellei, F Sebastiani… - The FEBS …, 2024 - Wiley Online Library
The identification of the coproporphyrin‐dependent heme biosynthetic pathway, which is
used almost exclusively by monoderm bacteria in 2015 by Dailey et al. triggered studies …
used almost exclusively by monoderm bacteria in 2015 by Dailey et al. triggered studies …