Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …

Catatonia is a psychomotor disorder featuring stupor, posturing, and echophenomena. This
Series paper examines the evidence for immune dysregulation in catatonia. Activation of the …

In 2007, a multifaceted syndrome, associated with anti-NMDA receptor autoantibodies
(NMDAR-AB) of immunoglobulin-G isotype, has been described, which variably consists of …

Multiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric
illness. While systemic autoimmune diseases are well-documented causes of …

Context Evidence for symptomatic convergence of schizophrenia and N-methyl-D-aspartate
glutamate receptor (NMDA-R) encephalitis highlights the need for an assessment of …

Objective: The aim of this study was to describe the clinical features and specificities of adult
male patients with NMDA receptor antibodies (NMDAr-Abs) encephalitis. Methods …

The identification of circulating autoantibodies against neuronal receptors in
neuropsychiatric disorders has fostered new conceptual and clinical frameworks. However …

Objective: To search for antibodies against neuronal cell surface proteins. Methods: Using
immunoprecipitation from neuronal cultures and tandem mass spectrometry, we identified …

Schizophrenia is a heterogeneous psychiatric disorder with a broad spectrum of clinical and
biological manifestations. Due to the lack of objective tests, the accurate diagnosis and …