Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …

Therapeutic mRNA vaccination is an attractive approach to trigger antitumor immunity.
However, the mRNA delivery technology for customized tumor vaccine is still limited. In this …

The complex gastrointestinal environment and the intestinal epithelial barrier constrain the
design and effectiveness of orally administered tumour vaccines. Here we show that outer …

Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …

Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems.
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …

The critical challenge for cancer vaccine‐induced T‐cell immunity is the sustained activation
of antigen cross‐presentation in antigen‐presenting cells (APCs) with innate immune …

Lung metastasis is challenging in patients with triple‐negative breast cancer (TNBC).
Surgery is always not available due to the dissemination of metastatic foci and most drugs …

Nanoparticle (NP)-based mRNA cancer vaccines hold great promise to realize personalized
cancer treatments. To advance this technology requires delivery formulations for efficient …

Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …