The sequential flow of electrons in the respiratory chain, from a low reduction potential
substrate to O2, is mediated by protein-bound redox cofactors. In mitochondria, hemes …

Heme is a ubiquitous and essential iron containing metallo-organic cofactor required for
virtually all aerobic life. Heme synthesis is initiated and completed in mitochondria, followed …

The appearance of heme, an organic ring surrounding an iron atom, in evolution forever
changed the efficiency with which organisms were able to generate energy, utilize gasses …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

Heme is the prosthetic group for cytochromes, which are directly involved in
oxidation/reduction reactions inside and outside the cell. Many cytochromes contain heme …

Covering: up to July 2008 A discussion of the literature concerning the synthesis, function,
and activity of hemec-containing proteins is presented. Comparison of the properties of …

Mitochondria contain two aqueous compartments: the matrix and the intermembrane space.
Whereas many of the biologic functions of the matrix were well characterized in the past, it …

The oxidative phosphorylation system contains four respiratory chain complexes that
connect the transport of electrons to oxygen with the establishment of an electrochemical …

Cytochromes c (cyt c) and c 1 are heme proteins that are essential for aerobic respiration.
Release of cyt c from mitochondria is an important signal in apoptosis initiation. Biogenesis …

The mitochondrial inner membrane plays central roles in bioenergetics and metabolism and
contains several established membrane protein complexes. Here, we report the …