Microbes typically live in complex habitats, where they need to rapidly adapt to continuously
changing growth conditions. To do so, they produce an astonishing array of natural products …

Abstract Background Pistachio (Pistacia vera L.) is one of the most important commercial nut
crops worldwide. It is a salt-tolerant and long-lived tree, with the largest cultivation area in …

The increased availability of whole genome sequences calls for quantitative models of
global gene expression, yet predicting gene expression patterns directly from genome …

ChIP-seq (Chromatin Immunoprecipitation followed by sequencing) is a high-throughput
technique to identify genomic regions that are bound in vivo by a particular protein, eg, a …

During cellular differentiation, enhancers transform overlapping gradients of transcription
factors (TFs) to highly specific gene expression patterns. However, the vast complexity of …

Proteins including transcription factors (TFs) and regulating enzymes search DNA for
specific sites by alternating 3D diffusion in cell nucleus space and 1D diffusion on DNA. The …

Transcription factors (TFs) bind to specific regions of DNA known as transcription factor
binding sites (TFBSs) and modulate gene expression by interacting with the transcriptional …

The motif discovery problem is becoming increasingly important for molecular biologists as
new sequencing technologies are producing large amounts of data, at rates which are …

Integrase catalytic domain (ICD) is an essential part in the retrovirus for integration reaction,
which enables its newly synthesized DNA to be incorporated into the DNA of infected cells …

Los últimos años han visto florecer y consolidarse a un extenso catálogo de metodologías
experimentales, las cuales han dado lugar a vastas cantidades de información biológica. La …