The incidence and/or prevalence of health problems associated with endocrine‐disruption
have increased. Many chemicals have endocrine‐disrupting properties, including bisphenol …

Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Genomic instability and alterations in gene expression are hallmarks of eukaryotic aging.
The yeast histone deacetylase Sir2 silences transcription and stabilizes repetitive DNA, but …

DNA methylation is a vital component of the epigenetic machinery that orchestrates changes
in multiple genes and helps regulate gene expression in all known vertebrates. We …

Lead occurs primarily in the inorganic form in the environment. Human exposure is mainly
via food and water, with some via air, dust and soil. In average adult consumers, lead dietary …

The aetiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. Free radicals derived …

Epigenetic modifications help orchestrate sweeping developmental, aging, and disease-
causing changes in phenotype by altering transcriptional activity in multiple genes spanning …

Clusterin, also known as apolipoprotein J, is a versatile chaperone molecule which contains
several amphipathic and coiled-coil α-helices, typical characteristics of small heat shock …

In the present review we summarize recent advances in the understanding of the interaction
between genetics and environmental factors involved in complex multi-factorial …

This review surveys the recent literature on the neurodevelopmental impacts of chemical
exposures during pregnancy. The review focuses primarily on chemicals of recent concern …