The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has
quickly become a global health emergency. Given the lack of specific anti-viral therapies, the …

Rheumatoid arthritis (RA) is a common inflammatory form of arthritis leading to the
progressive bone and joint destruction. Many factors are closely involved in the pathology of …

Objectives Age-associated B cells (ABCs) are a recently identified B cell subset, whose
expansion has been increasingly linked to the pathogenesis of autoimmune disorders. This …

Rheumatoid arthritis (RA) is a common autoimmune disease leading to pain, disability, and
even death. Although studies have revealed that aberrant activation of STING was …

Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …

In recent years, with the advancement of next-generation sequencing (NGS) technology,
gene panel tests have been approved in the field of cancer diseases, and approaches to …

Background Rheumatoid arthritis (RA) is a known intractable chronic inflammatory disease
of synovial joints characterized by hyperplasia and consecutive inflammation with a high …

Immune-targeted therapies have efficacy for treatment of autoinflammatory diseases. For
example, treatment with the T cell–specific anti-CD3 antibody teplizumab delayed disease …

Early diagnosis of rheumatoid arthritis (RA) is crucial to prevent deterioration and improve
the prognosis of disease outcome. However, current clinical diagnostic methods are unable …

Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints,
causing irreversible cartilage, synovium, and bone degradation. During the course of the …