Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by
widespread intravascular activation of coagulation that can be caused by infectious insults …

Standard laboratory coagulation tests (SLTs) such as prothrombin time/international
normalized ratio or partial thromboplastin time are frequently used to assess coagulopathy …

The purpose of this study was to assess the change of platelet and fibrinogen concentrations
and the change of activities of prothrombin and factors V and VII when major surgical blood …

Background: Acute traumatic coagulopathy (ATC) is an impairment of hemostasis that
occurs early after injury and is associated with a 4‐fold higher mortality, increased …

Abstract Background Thromboelastometry (ROTEM®) might be useful to detect
intraoperative coagulation disorders early in major paediatric surgery. This observational …

Purpose To review the pathophysiology of coagulopathy in massively transfused, adult and
previously hemostatically competent patients in both elective surgical and trauma settings …

Numerous published guidelines encourage appropriate use of fresh frozen plasma (FFP).
However, adherence is documented as poor. Therefore, we sought to determine the …

An obstetric hemorrhage may occur before or after delivery, but more than 80% of cases
occur postpartum. Worldwide, a massive obstetric hemorrhage, resulting from the failure of …

A trauma patient's survival depends on the ability to control 2 opposing conditions, bleeding
at the early phase and thrombosis at a late phase of trauma. The mixed existence of …

Hemorrhage is a major cause of trauma deaths. Coagulopathy exacerbates hemorrhage
and is commonly seen during major trauma resuscitation, suggesting that current practice of …