Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

The renin-angiotensin system (RAS) plays a crucial role in cardiovascular regulations and
its modulation is a challenging target for the vast majority of cardioprotective strategies …

Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies.
Oxidative stress has been validated as a critical event involved in DOX-induced …

Anthracyclines, a class of drugs considered as most effective anticancer drugs, used in the
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …

Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its
long-term use can cause neurobiological side-effects associated with depression. Omega-3 …

Chemotherapy-related cognitive impairment (CRCI) or “chemo brain” is a devastating
neurotoxic sequela of cancer-related treatments, especially for the elderly individuals. Here …

Many patients who have received chemotherapy to treat cancer experience depressive-and
anxiety-like symptoms or cognitive impairment. However, despite the evidence for this, the …

Doxorubicin (DOX) is known to cause cognitive impairments in patients submitted to long-
term chemotherapy (deficits also known as chemobrain). The present study investigated …

In the past few years possible mechanisms that link diabetes and depression have been
found. One of these mechanisms is the increase in lipid peroxidation and decrease in …

This investigation was designed to determine the effect of melatonin supplementation on
mental health parameters, metabolic and genetic profiles in patients under methadone …