Clinical viability of boron neutron capture therapy for personalized radiation treatment

D Skwierawska, JA López-Valverde, M Balcerzyk… - Cancers, 2022 - mdpi.com
Simple Summary Usually, for dose planning in radiotherapy, the tumor is delimited as a
volume on the image of the patient together with other clinical considerations based on …

The synthesis and use of boronated amino acids for boron neutron capture therapy

GW Kabalka, ML Yao - Anti-Cancer Agents in Medicinal …, 2006 - ingentaconnect.com
The treatment of cancer remains one of the most challenging problems for humanity. Boron
neutron capture therapy (BNCT) is a binary approach for cancer treatment that is particularly …

[HTML][HTML] Targeting the organelle for radiosensitization in cancer radiotherapy

X Sun, L Wu, L Du, W Xu, M Han - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Radiotherapy is a well-established cytotoxic therapy for local solid cancers, utilizing high-
energy ionizing radiation to destroy cancer cells. However, this method has several …

30 Inorganic pharmaceuticals

PJ Blower - Annual Reports Section" A"(Inorganic Chemistry), 2004 - pubs.rsc.org
30 Inorganic pharmaceuticals - Annual Reports Section "A" (Inorganic Chemistry) (RSC
Publishing) DOI:10.1039/B312109G Royal Society of Chemistry View PDF VersionPrevious …

Intracellular uptake of a new boronated porphyrin EC032

T Tsurubuchi, T Yamamoto, K Nakai… - Applied Radiation and …, 2009 - Elsevier
We measured the toxicity and intracellular uptake of a newly developed boronated porphyrin
EC032, and verified the fluorescence-based boron concentration measuring methods …

[PDF][PDF] Physical Bases of Boron Neutron Capture Therapy, Dosimetry, and Its Mechanisms of Action—A Critical Overview of the Literature

D Skwierawska, M Balcerzyk, JA Lopez-Valverde… - 2021 - scholar.archive.org
The success of boron neutron capture therapy (BNCT) depends mainly on sufficient spatial
biodistribution of boron (10B) localized around or within neoplastic cells to produce a high …

[PDF][PDF] A study by transmission electron microscopy on human glioblastoma cells after BNCT

KJ Chun, WJ Kim, HW Oh - 2006 - kns.org
Irradiation of the stable isotope 10B with biologically low effective thermal neutrons is
followed by a transmutation of 10B to 7Li and an emission of high energy alpha particles …