The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications

A Quarteroni, A Manzoni, C Vergara - Acta Numerica, 2017 - cambridge.org
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …

[图书][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications

A Quarteroni, A Manzoni, C Vergara - 2019 - books.google.com
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …

Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting

MS Zakaria, F Ismail, M Tamagawa, AFA Aziz… - Medical & biological …, 2017 - Springer
Even though the mechanical heart valve (MHV) has been used routinely in clinical practice
for over 60 years, the occurrence of serious complications such as blood clotting remains to …

lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

PC Africa, I Fumagalli, M Bucelli, A Zingaro… - Computer Physics …, 2024 - Elsevier
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy

P van Ooij, WV Potters, J Collins, M Carr, J Carr… - Annals of biomedical …, 2015 - Springer
There exists considerable controversy surrounding the timing and extent of aortic resection
for patients with BAV disease. Since abnormal wall shear stress (WSS) is potentially …

Comparison of hemodynamic and structural indices of ascending thoracic aortic aneurysm as predicted by 2-way FSI, CFD rigid wall simulation and patient-specific …

V Mendez, M Di Giuseppe, S Pasta - Computers in biology and medicine, 2018 - Elsevier
Patient-specific computational modeling is increasingly being used to predict structural and
hemodynamic parameters, especially when current clinical tools are not accessible. Indeed …

Computational comparison of regional stress and deformation characteristics in tricuspid and bicuspid aortic valve leaflets

K Cao, P Sucosky - International journal for numerical methods …, 2017 - Wiley Online Library
The bicuspid aortic valve (BAV) is the most common congenital valvular defect and a major
risk factor for secondary calcific aortic valve disease. While hemodynamics is presumed to …

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

M Fedele, E Faggiano, L Dedè, A Quarteroni - Biomechanics and modeling …, 2017 - Springer
In this paper, we propose a full computational framework to simulate the hemodynamics in
the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta …

Simulations of morphotype-dependent hemodynamics in non-dilated bicuspid aortic valve aortas

K Cao, SK Atkins, A McNally, J Liu, P Sucosky - Journal of biomechanics, 2017 - Elsevier
Bicuspid aortic valves (BAVs) generate flow abnormalities that may promote aortopathy.
While positive helix fraction (PHF) index, flow angle (θ), flow displacement (d) and wall …

Volumetric quantification of absolute local normalized helicity in patients with bicuspid aortic valve and aortic dilatation

J Garcia, AJ Barker, JD Collins… - Magnetic resonance in …, 2017 - Wiley Online Library
Purpose Absolute local normalized helicity (LNH) can differentiate flow alterations in the
aorta between healthy controls and bicuspid aortic valve (BAV) patients. Methods A total of …