Developing a model-driven workflow for the digital design of small-scale batch cooling crystallisation with the antiviral lamivudine

T Pickles, C Mustoe, C Boyle, J Cardona, CJ Brown… - …, 2024 - pubs.rsc.org
We present a workflow that uses digital tools to optimise the experimental approach and
maximise the efficiency in achieving the required process parameters for a desired set of …

Integration of a model-driven workflow into an industrial pharmaceutical facility: supporting process development of API crystallisation

T Pickles, V Svoboda, I Marziano, CJ Brown… - …, 2024 - pubs.rsc.org
Developing crystallisation processes in the pharmaceutical industry is material and resource
intensive due to the large design space, ie many different process parameters and …