New trends in peptide-based anti-biofilm strategies: a review of recent achievements and bioinformatic approaches

P Jorge, A Lourenco, MO Pereira - Biofouling, 2012 - Taylor & Francis
Antimicrobial peptides (AMPs) have a broad spectrum of activity and unspecific mechanisms
of action. Therefore, they are seen as valid alternatives to overcome clinically relevant …

Computational drug repurposing: current trends

B Karaman, W Sippl - Current medicinal chemistry, 2019 - ingentaconnect.com
Biomedical discovery has been reshaped upon the exploding digitization of data which can
be retrieved from a number of sources, ranging from clinical pharmacology to …

Gene ontology consortium: going forward

Gene Ontology Consortium - Nucleic acids research, 2015 - academic.oup.com
Abstract The Gene Ontology (GO; http://www. geneontology. org) is a community-based
bioinformatics resource that supplies information about gene product function using …

The Reactome pathway knowledgebase

D Croft, AF Mundo, R Haw, M Milacic… - Nucleic acids …, 2014 - academic.oup.com
Abstract Reactome (http://www. reactome. org) is a manually curated open-source open-
data resource of human pathways and reactions. The current version 46 describes 7088 …

Proteoform: a single term describing protein complexity

LM Smith, NL Kelleher - Nature methods, 2013 - nature.com
A surprise revealed by the success of the human genome project was the lower-than-
anticipated number of genes identified:∼ 20,300, rather than the∼ 100,000 estimated 1 …

Activities at the universal protein resource (UniProt)

UniProt Consortium - Nucleic acids research, 2014 - academic.oup.com
The mission of the Universal Protein Resource (UniProt)(http://www. uniprot. org) is to
provide the scientific community with a comprehensive, high-quality and freely accessible …

An open source knowledge graph ecosystem for the life sciences

TJ Callahan, IJ Tripodi, AL Stefanski, L Cappelletti… - Scientific Data, 2024 - nature.com
Translational research requires data at multiple scales of biological organization.
Advancements in sequencing and multi-omics technologies have increased the availability …

The ChEMBL database as linked open data

EL Willighagen, A Waagmeester, O Spjuth… - Journal of …, 2013 - Springer
Background Making data available as Linked Data using Resource Description Framework
(RDF) promotes integration with other web resources. RDF documents can natively link to …

An open annotation ontology for science on web 3.0

P Ciccarese, M Ocana, LJ Garcia Castro, S Das… - Journal of biomedical …, 2011 - Springer
Background There is currently a gap between the rich and expressive collection of
published biomedical ontologies, and the natural language expression of biomedical papers …

Protein Ontology (PRO): enhancing and scaling up the representation of protein entities

DA Natale, CN Arighi, JA Blake, J Bona… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Protein Ontology (PRO; http://purl. obolibrary. org/obo/pr) formally defines and
describes taxon-specific and taxon-neutral protein-related entities in three major areas …