Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Addictions neuroclinical assessment: a neuroscience-based framework for addictive disorders

LE Kwako, R Momenan, RZ Litten, GF Koob… - Biological …, 2016 - Elsevier
This article proposes a heuristic framework for the Addictions Neuroclinical Assessment that
incorporates key functional domains derived from the neurocircuitry of addiction. We review …

Humans primarily use model-based inference in the two-stage task

C Feher da Silva, TA Hare - Nature Human Behaviour, 2020 - nature.com
Distinct model-free and model-based learning processes are thought to drive both typical
and dysfunctional behaviours. Data from two-stage decision tasks have seemingly shown …

Computational psychiatry as a bridge from neuroscience to clinical applications

QJM Huys, TV Maia, MJ Frank - Nature neuroscience, 2016 - nature.com
Translating advances in neuroscience into benefits for patients with mental illness presents
enormous challenges because it involves both the most complex organ, the brain, and its …

The anterior cingulate cortex predicts future states to mediate model-based action selection

T Akam, I Rodrigues-Vaz, I Marcelo, X Zhang… - Neuron, 2021 - cell.com
Behavioral control is not unitary. It comprises parallel systems, model based and model free,
that respectively generate flexible and habitual behaviors. Model-based decisions use …

When habits are dangerous: alcohol expectancies and habitual decision making predict relapse in alcohol dependence

M Sebold, S Nebe, M Garbusow, M Guggenmos… - Biological …, 2017 - Elsevier
Background Addiction is supposedly characterized by a shift from goal-directed to habitual
decision making, thus facilitating automatic drug intake. The two-step task allows …

[HTML][HTML] Compulsivity-related neurocognitive performance deficits in gambling disorder: A systematic review and meta-analysis

T Van Timmeren, JG Daams, RJ Van Holst… - Neuroscience & …, 2018 - Elsevier
Compulsivity is a core feature of addictive disorders, including gambling disorder. However,
it is unclear to what extent this compulsive behavior in gambling disorder is associated with …

Simple plans or sophisticated habits? State, transition and learning interactions in the two-step task

T Akam, R Costa, P Dayan - PLoS computational biology, 2015 - journals.plos.org
The recently developed 'two-step'behavioural task promises to differentiate model-based
from model-free reinforcement learning, while generating neurophysiologically-friendly …

Computational models of drug use and addiction: A review.

JA Mollick, H Kober - Journal of abnormal psychology, 2020 - psycnet.apa.org
In this brief review, we describe current computational models of drug-use and addiction that
fall into 2 broad categories: mathematically based models that rely on computational …

Current limits of experimental research into habits and future directions

P Watson, S De Wit - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•Insensitivity to devaluation could be due to habits or weak goal-directed
control.•Limited direct evidence for habits as a function of behavioral repetition in …