The RNase T2 family consists of evolutionarily conserved endonucleases that express in
many different species, including animals, plants, protozoans, bacteria, and viruses. The …

The link between cancer development or progression and immune system dysregulation
has long been established. Virtually every cell type belonging to both the innate and …

RALY is a member of the heterogeneous nuclear ribonucleoproteins, a family of RNA-
binding proteins generally involved in many processes of mRNA metabolism. No …

Arginyltransferase ATE1 mediates posttranslational arginylation and plays key roles in
multiple physiological processes. ATE1 utilizes arginyl (Arg)-tRNA Arg as the donor of Arg …

Clear cell renal cell carcinoma (ccRCC), the most common malignant subtype of renal cell
carcinoma, is characterized by the accumulation of lipid droplets in the cytoplasm. RNASET2 …

In recent years, there has been a growing interest in developing innovative anticancer
therapies targeting the tumor microenvironment (TME). The TME is a complex and dynamic …

Ovarian cancer represents one of the most malignant gynecological cancers worldwide, with
an overall 5-year survival rate, being locked in the 25–30% range in the last decade. Cancer …

Activation of microglial cells accompanies the progression of many neurodegenerative
disorders, including Alzheimer's disease (AD). Development of molecular imaging tools …

Mutations in the gene of human RNase T2 are associated with white matter disease of the
human brain. Although brain abnormalities (bilateral temporal lobe cysts and multifocal …

RNASET2 is a ubiquitously expressed acidic ribonuclease that has been implicated in
diverse pathophysiological processes including tumorigeneis, vitiligo, asthenozoospermia …