The neurochemistry of autism
R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …
neurodevelopmental conditions characterized by impaired social interaction and …
Nicotinic ACh receptors as therapeutic targets in CNS disorders
KT Dineley, AA Pandya, JL Yakel - Trends in pharmacological sciences, 2015 - cell.com
The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability by acting on the
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …
Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
HO Kalkman, D Feuerbach - Cellular and molecular life sciences, 2016 - Springer
The clinical development of selective alpha-7 nicotinic acetylcholine receptor (α7 nAChR)
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …
Autism: Pathophysiology and promising herbal remedies
Autism is a comprehensive growth abnormality in which social skills, language,
communication, and behavioral skills are developed with delay and as diversionary. The …
communication, and behavioral skills are developed with delay and as diversionary. The …
Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …
executive functioning and communication deficits with those described in several …
A machine learning approach for understanding the metabolomics response of children with autism spectrum disorder to medical cannabis treatment
JC Quillet, M Siani-Rose, R McKee, B Goldstein… - Scientific Reports, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting behavior,
communication, social interaction and learning abilities. Medical cannabis (MC) treatment …
communication, social interaction and learning abilities. Medical cannabis (MC) treatment …
Potential therapeutic use of the ketogenic diet in autism spectrum disorders
E Napoli, N Dueñas, C Giulivi - Frontiers in pediatrics, 2014 - frontiersin.org
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with
glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as …
glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as …
Systematic review and meta-analysis: pharmacological and nonpharmacological interventions for persistent nonepisodic irritability
Objective This meta-analysis examined the efficacy of available pharmacological and
nonpharmacological interventions for irritability among youth with autism spectrum disorder …
nonpharmacological interventions for irritability among youth with autism spectrum disorder …
[HTML][HTML] Galantamine alleviates inflammation and insulin resistance in patients with metabolic syndrome in a randomized trial
BACKGROUND. Metabolic syndrome (MetS) is an obesity-driven condition of pandemic
proportions that increases the risk of type 2 diabetes and cardiovascular disease …
proportions that increases the risk of type 2 diabetes and cardiovascular disease …
N-acetylcysteine as an adjunctive therapy to risperidone for treatment of irritability in autism: a randomized, double-blind, placebo-controlled clinical trial of efficacy …
M Nikoo, H Radnia, M Farokhnia… - Clinical …, 2015 - journals.lww.com
Objectives According to the proposed interference of N-acetylcysteine (NAC) with
pathophysiologic processes of autistic disorders (ADs), we aimed to assess the …
pathophysiologic processes of autistic disorders (ADs), we aimed to assess the …