Aging induces molecular, cellular and functional changes in the adult brain that drive
cognitive decline and increase vulnerability to dementia-related neurodegenerative …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and
growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity …

Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

Stressful experiences, both physical and psychological, that are overwhelming (ie,
inescapable and unpredictable), can measurably affect subsequent neuronal properties and …

Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …

In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …

Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …