Alcohol dehydrogenases as catalysts in organic synthesis

AS de Miranda, CDF Milagre, F Hollmann - Frontiers in Catalysis, 2022 - frontiersin.org
Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …

Effect of para‐Substituents on meso‐Functionalized Oxidovanadium(IV) Porphyrins as Catalysts for Oxygen Atom Transfer Mediated Oxidation of Benzoin to Benzil …

MR Maurya, V Prakash, I Yadav… - European Journal of …, 2023 - Wiley Online Library
Systematic analysis of the effect of para‐substituents (H, Cl, Br and OMe) on the meso‐
phenyl group in vanadyl meso‐tetraphenylporphyrins ([VIVO (TPP)](R= H, 1),[VIVO …

Catalytic Strategies to Enantiopure Benzoins: Past and Future

L De Luca, A Mezzetti - Synthesis, 2020 - thieme-connect.com
The catalytic strategies developed so far for the synthesis of enantiomerically pure benzoins
are reviewed. Particular attention is given to their substrate scope and limitations. Finally …

Asymmetric Synthesis of Chiral Benzoins Enabled by Engineered Ketoreductase-Catalyzed Stereoselective Reduction of Benzils

Y Ye, Y Tao, P Hu, Y Zhang, L Zhang… - ACS Sustainable …, 2024 - ACS Publications
Chiral benzoins are versatile precursors to various valuable synthons such as chiral
hydrobenzoins and chiral vicinal amino alcohols. In principle, ketoreductase (KRED) …

Isothiourea-catalysed sequential kinetic resolution of acyclic (±)-1, 2-diols

S Harrer, MD Greenhalgh, RM Neyyappadath… - Synlett, 2019 - thieme-connect.com
The isothiourea-catalysed acylative kinetic resolution of a range of acyclic (±)-1, 2-diols
using 1 mol% of catalyst under operationally simple conditions is reported. Significantly, the …

Characterization of two novel alcohol short-chain dehydrogenases/reductases from Ralstonia eutropha H16 capable of stereoselective conversion of bulky substrates

Z Magomedova, A Grecu, CW Sensen, H Schwab… - Journal of …, 2016 - Elsevier
Biocatalysis has significant advantages over organic synthesis in the field of chiral molecule
production and several types of stereoselective enzymes are already in use in industrial …

Chiral Benzoins via Asymmetric Transfer Hemihydrogenation of Benzils: The Detail that Matters

LD Luca, A Mezzetti - The Journal of organic chemistry, 2020 - ACS Publications
The synthesis of enantiomerically pure benzoins by hydrogenation of readily available
benzils has been long thwarted by their base-sensitivity. We show here that an iron (II) …

Chiral Modification of Ferrite Nanoparticles for Oxidative Kinetic Resolution of Benzoins

PK Gupta, N Kumar, AB Majumder… - Asian Journal of …, 2023 - Wiley Online Library
We report the surface modification of ferrite nanoparticles (MFe2O4 NPs; M= Mn, Fe, Co, Ni,
Cu, Zn) with chiral surfactants derived from cinchona alkaloids. The successful synthesis of …

[HTML][HTML] Efficient Stereoselective Biotransformation of Prochiral Carbonyls by Endophytic Fungi from Handroanthus impetiginosus

VHP dos Santos, MVP de Souza, MM Victor, VB Riatto… - SynBio, 2024 - mdpi.com
Endophytic microorganisms are promising sources for new biocatalysts as they must deal
with their host plants' chemicals by developing adaptative strategies, such as enzymatic …

Reaction control in heterogeneous catalysis using montmorillonite: switching between acid-catalysed and red-ox processes

JA Morales-Serna, BA Frontana-Uribe, R Olguín… - RSC …, 2016 - pubs.rsc.org
The use of montmorillonite, modified with a super-acid (CF3SO3H), in the presence of
hydroquinone as a radical scavenger and under a nitrogen atmosphere, induced the …