The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily
using positron emission tomography coupled to computed tomography (PET/CT) with the …

The ongoing obesity pandemic generates a constant need to develop new therapeutic
strategies to restore the energy balance. Therefore, the concept of activating brown adipose …

Abstract Purpose of Review New treatment approaches to weight loss and weight loss
maintenance in humans are critical. Given its potential role in stimulating energy …

In the midst of an obesity epidemic, the promotion of brown adipose tissue (BAT) function
and the browning of white adipose tissue (WAT) have emerged as promising therapeutic …

Discovery of the presence of brown adipose tissue (BAT) in newborn babies and adult
humans, especially constitutively active brown fat or inducible beige fat, has led to the …

Adipose tissue is an endocrine organ with high metabolic activity. Countless adipose tissue-
secreted adipokines and lipokines, as well as peptides and lipids with biological activity …

Stress affects core body temperature (T c). Many kinds of stress induce transient,
monophasic hyperthermia, which diminishes gradually if the stressor is terminated. Stronger …

Obesity is a worldwide health problem due to the imbalance of energy intake and energy
expenditure. Irisin, a newly identified exercise‐responsive myokine, which is produced by …

Promotion of brown adipose tissue (BAT) activity or browning of white adipose tissue has
shown great potential as anti-obesity strategy in numerous preclinical models. The discovery …

Mitochondria are capable of detecting cellular insults and orchestrating inflammatory
responses. Mitochondrial reactive oxygen species (mtROS) are intermediates that trigger …