MicroRNAs (miRNAs) are a group of small noncoding RNA molecules with significant
capacity to regulate the gene expression at the post-transcriptional level in a sequence …

In the search for new biomarkers and therapeutic targets for infectious diseases, several
molecules have been investigated. Small RNAs, known as microRNAs (miRs), are important …

Adipose‐derived stem cells (ASC) are said to have a pivotal role in wound healing.
Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as …

Leishmaniasis is one of the major neglected tropical diseases, for which no vaccines exist.
Chemotherapy is hampered by limited efficacy coupled with development of resistance and …

American Tegumentary Leishmaniasis (ATL) is an endemic disease in Latin America, mainly
caused in Brazil by Leishmania (Viannia) braziliensis. Clinical manifestations vary from mild …

Chronic itch is one of the disturbing symptoms of inflammatory skin diseases. Kappa opioid
receptor agonists are effective in suppressing scratching in mice against different …

The triggering receptor expressed on myeloid cells 1 (TREM-1) is a receptor of the innate
immune system, expressed mostly by myeloid cells and primarily associated with pro …

Non-coding RNAs (ncRNAs) including microRNAs (miRs) and long non-coding RNAs
(lncRNAs) have emerged as key regulators of gene expression in immune cells …

Mastitis is known as intramammary inflammation, which has a multifactorial complex
phenotype. However, the underlying molecular pathogenesis of mastitis remains poorly …

L.(viannia) braziliensis infection causes American Tegumentary Leishmaniasis (ATL), with
prolonged time to healing lesions. The potent inflammatory response developed by the host …