BACKGROUND The advances in the world of IVF during the last decades have been rapid
and impressive and culture media play a major role in this success. Until the 1980s fertility …

STUDY QUESTION Is it important that end-users know the composition of human embryo
culture media? SUMMARY ANSWER We argue that there is as strong case for full …

INTRODUCTION When an egg is fertilized by a sperm, the chromosomes of the mother and
the father become united, and a genetically unique embryo starts to form. A healthy embryo …

We examined different weight ranges and hormone dosages to determine superovulation
protocols for 6 mouse strains commonly used in genetic engineering: C57BL/6NHsd, B6 …

Vigorous sperm motility, including the transition from progressive to hyperactivated motility
that occurs in the female reproductive tract, is required for normal fertilization in mammals …

Superovulation is a reproductive technique generally used to produce genetically
engineered mice. Superovulation in mice involves the administration of equine chorionic …

Although substantial evidence exists that sperm ATP production via glycolysis is required for
mammalian sperm function and male fertility, conflicting reports involving multiple species …

Abstract Previously we established Zygote Electroporation of Nucleases (ZEN) technology
as an efficient and high-throughput way to generate genetically modified mouse models …

Assisted reproductive technologies (ART) account for 1–6% of births in developed countries.
While most children conceived are healthy, increases in birth and genomic imprinting …

Embryonic morphogenesis is strictly dependent on tight spatiotemporal control of
developmental gene expression, which is typically achieved through the concerted activity of …