[HTML][HTML] GABAergic circuits drive focal seizures

E Dossi, G Huberfeld - Neurobiology of Disease, 2023 - Elsevier
Epilepsy is based on abnormal neuronal activities that have historically been suggested to
arise from an excess of excitation and a defect of inhibition, or in other words from an …

Altered neuronal lactate dehydrogenase A expression affects cognition in a sex-and age-dependent manner

AK Frame, JL Sinka, M Courchesne, RA Muhammad… - Iscience, 2024 - cell.com
The astrocyte-neuron lactate shuttle (ANLS) model posits that astrocyte-generated lactate is
transported to neurons to fuel memory processes. However, neurons express high levels of …

Effects of chronic insecticide exposure on neuronal network development in vitro in rat cortical cultures

LVJ van Melis, AM Peerdeman, CA González… - Archives of …, 2024 - Springer
Developmental exposure to carbamates, organophosphates, and pyrethroids has been
associated with impaired neurodevelopmental outcomes. Sex-specific differences following …

[HTML][HTML] Reduced 17β-estradiol following ovariectomy induces mitochondrial dysfunction and degradation of synaptic proteins in the entorhinal cortex

OJ Olajide, AAB Burrowes, IF da Silva, A Bergdahl… - Neuroscience, 2025 - Elsevier
Reductions in circulating estrogens can contribute to cognitive decline, in part by impairing
mitochondrial function within the hippocampal region. The entorhinal cortex provides the …

Maturation of the Endocannabinoid System in the Medial Prefrontal Cortex and the Effect of Perinatal Cananbinoid Exposure

MM Green - 2023 - search.proquest.com
The endocannabinoid system (ECS) is a widespread neuromodulatory system that is
present from early stages of prenatal development and plays a critical role in central nervous …

CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion

S Norberto, HB Assalin, D Guadagnini… - Frontiers in …, 2023 - frontiersin.org
Introduction Cdc2-like kinase (CLK2) is a member of CLK kinases expressed in
hypothalamic neurons and is activated in response to refeeding, leptin, or insulin. Diet …