The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery

SE Grogans, E Bliss-Moreau, KA Buss, LA Clark… - Neuroscience & …, 2023 - Elsevier
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

Cross-species anxiety tests in psychiatry: pitfalls and promises

DR Bach - Molecular Psychiatry, 2022 - nature.com
Behavioural anxiety tests in non-human animals are used for anxiolytic drug discovery, and
to investigate the neurobiology of threat avoidance. Over the past decade, several of them …

[HTML][HTML] Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo

M Torres-Ruiz, M de Alba González, M Morales… - Science of The Total …, 2023 - Elsevier
Nanoplastics (NP) are present in aquatic and terrestrial ecosystems. Humans can be
exposed to them through contaminated water, food, air, or personal care products …

Rodent tests of depression and anxiety: Construct validity and translational relevance

S Gencturk, G Unal - Cognitive, Affective, & Behavioral Neuroscience, 2024 - Springer
Behavioral testing constitutes the primary method to measure the emotional states of
nonhuman animals in preclinical research. Emerging as the characteristic tool of the …

VR for studying the neuroscience of emotional responses

M Andreatta, MH Winkler, P Collins, D Gromer… - Virtual Reality in …, 2023 - Springer
Emotions are frequently considered as the driving force of behavior, and psychopathology is
often characterized by aberrant emotional responding. Emotional states are reflected on a …

A Critical Review of Zebrafish Neurological Disease Models− 2. Application: Functional and Neuroanatomical Phenotyping Strategies and Chemical Screens

EA Burton, HA Burgess - Oxford open neuroscience, 2023 - academic.oup.com
Extensive phylogenetic conservation of molecular pathways and neuroanatomical
structures, associated with efficient methods for genetic modification, have been exploited …

Effects of 700 and 3500 MHz 5G radiofrequency exposure on developing zebrafish embryos

M Torres-Ruiz, OJ Suárez, V López, P Marina… - Science of The Total …, 2024 - Elsevier
Telecommunications industries are rapidly deploying the fifth generation (5G) spectrum and
there is public concern about the safety and health impacts of this type of Radio Frequency …

Reliability of repeated exposure to the human elevated plus-maze in virtual reality: Behavioral, emotional, and autonomic responses

SV Biedermann, L Roth, D Biedermann… - Behavior Research …, 2024 - Springer
Abstract Approach–avoidance conflicts are a hallmark of anxiety-related behaviors. A gold
standard for assessing anxiety-related behaviors in rodents is the elevated plus-maze …

Roadbumps at the Crossroads of Integrating Behavioral and In Vitro Approaches for Neurotoxicity Assessment

GJ Harry, S Mcbride, SK Witchey… - Frontiers in …, 2022 - frontiersin.org
With the appreciation that behavior represents the integration and complexity of the nervous
system, neurobehavioral phenotyping and assessment has seen a renaissance over the last …

A comparative analysis of Danionella cerebrum and zebrafish (Danio rerio) larval locomotor activity in a light-dark test

N Lindemann, L Kalix, J Possiel, R Stasch… - Frontiers in Behavioral …, 2022 - frontiersin.org
The genus Danionella comprises some of the smallest known vertebrate species and is
evolutionary closely related to the zebrafish, Danio rerio. With its optical translucency, rich …