The abortive infection functions of CRISPR-Cas and Argonaute

Y Chen, Z Zeng, Q She, W Han - Trends in microbiology, 2023 - cell.com
CRISPR-Cas and prokaryotic Argonaute (pAgo) are nucleic acid (NA)-guided defense
systems that protect prokaryotes against the invasion of mobile genetic elements. Previous …

[HTML][HTML] RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2

JPK Bravo, T Hallmark, B Naegle, CL Beisel… - Nature, 2023 - nature.com
Cas12a2 is a CRISPR-associated nuclease that performs RNA-guided, sequence-
nonspecific degradation of single-stranded RNA, single-stranded DNA and double-stranded …

Investigations of Prokaryotic Defense Systems

H Domgaard - 2022 - search.proquest.com
Bacteria are constantly threatened with infection by mobile genetic elements (MGE) such as
bacteriophage and plasmids. Bacteriophage and plasmids require the bacteria's cellular …