Release and activity of histone in diseases
R Chen, R Kang, XG Fan, D Tang - Cell death & disease, 2014 - nature.com
Histones and their post-translational modifications have key roles in chromatin remodeling
and gene transcription. Besides intranuclear functions, histones act as damage-associated …
and gene transcription. Besides intranuclear functions, histones act as damage-associated …
[HTML][HTML] Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders
The extracellular matrix proteoglycan (ECM) perlecan, also known as heparan sulfate
proteoglycan 2 or HSPG2, is one of the largest (> 200 nm) and oldest (> 550 M years) …
proteoglycan 2 or HSPG2, is one of the largest (> 200 nm) and oldest (> 550 M years) …
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy
Global gene expression profiling is used to generate novel insight into a variety of disease
states. Such studies yield a bewildering number of data points, making it a challenge to …
states. Such studies yield a bewildering number of data points, making it a challenge to …
α-actinin-4 is required for normal podocyte adhesion
SV Dandapani, H Sugimoto, BD Matthews… - Journal of Biological …, 2007 - ASBMB
Mutations in the α-actinin-4 gene ACTN4 cause an autosomal dominant human kidney
disease. Mice deficient in α-actinin-4 develop a recessive phenotype characterized by …
disease. Mice deficient in α-actinin-4 develop a recessive phenotype characterized by …
Reconstruction of muscle fascicle‐like tissues by anisotropic 3d patterning
Tissue engineering of skeletal muscle has been proposed as a potential regenerative
treatment for extensive muscle damage. In this regard, the highly organized structure of …
treatment for extensive muscle damage. In this regard, the highly organized structure of …
The glycosaminoglycan side chains and modular core proteins of heparan sulphate proteoglycans and the varied ways they provide tissue protection by regulating …
BL Farrugia, J Melrose - International Journal of Molecular Sciences, 2023 - mdpi.com
This review examines the roles of HS–proteoglycans (HS–PGs) in general, and, in
particular, perlecan and syndecan as representative examples and their interactive ligands …
particular, perlecan and syndecan as representative examples and their interactive ligands …
The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy
During tumor growth and angiogenesis there is a dynamic remodeling of tissue architecture
often accompanied by the release of extracellular matrix constituents full of biological …
often accompanied by the release of extracellular matrix constituents full of biological …
Functional role of the interaction between polysialic acid and extracellular histone H1
Polysialic acid (PSA) is a large and highly negatively charged glycan that plays crucial roles
in nervous system development and function in the adult. It has been suggested to facilitate …
in nervous system development and function in the adult. It has been suggested to facilitate …
Muscle satellite cell proliferation and association: new insights from myofiber time-lapse imaging
AL Siegel, PK Kuhlmann, DDW Cornelison - Skeletal muscle, 2011 - Springer
Background As the resident stem cells of skeletal muscle, satellite cells are activated by
extracellular cues associated with local damage. Once activated, satellite cells will re-enter …
extracellular cues associated with local damage. Once activated, satellite cells will re-enter …
[HTML][HTML] Role of skeletal muscle proteoglycans during myogenesis
E Brandan, J Gutierrez - Matrix Biology, 2013 - Elsevier
Skeletal muscle formation during development and the adult mammal consists of a highly
organised and regulated the sequence of cellular processes intending to form or repair …
organised and regulated the sequence of cellular processes intending to form or repair …