Aims This paper aimed to review how scientific knowledge about the human psychobiology
of MDMA has developed over time. Methods In this paper, the empirical findings from earlier …

Serotonergic neurotoxicity following MDMA is well-established in laboratory animals, and
neuroimaging studies have found lower serotonin transporter (SERT) binding in abstinent …

Abstract MDMA (“ecstasy”) is widely used as a recreational drug, although there has been
some debate about its neurotoxic effects in humans. However, most studies have …

Methylenedioxymethamphetamine (MDMA,“Ecstasy”) is a serotonin-and noradrenaline-
releasing substance, currently among the most widely used illicit substances worldwide. In …

A recent focus of addiction research has been on the effect of drug exposure on the neural
processes that mediate the acquisition and performance of goal-directed instrumental …

Context MDMA (3, 4-methylenedioxymethamphetamine, also popularly known as “ecstasy”)
is a popular recreational drug that produces loss of serotonin axons in animal models …

MDMA/Ecstasy has had a resurgence in popularity, with recent supplies comprising higher
strength MDMA, potentially leading to increased drug-related harm. Neurocognitive …

Stimulant dependence is associated with neuropsychological impairments. Here, we
summarize and integrate the existing neuroimaging literature on the neural substrates of …

Oscillations in brain activities with periods of minutes to hours may be critical for normal
mood behaviors. Ultradian (faster than circadian) rhythms of mood behaviors and …

Abstract Background 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) is a widely
used entactogenic drug known to impair cognitive functions on the long-run. Both …