The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Exposure to a variety of environmental factors such as salinity, drought, metal toxicity,
extreme temperature, air pollutants, ultraviolet‐B (UV‐B) radiation, pesticides, and pathogen …

Osteoarthritis (OA) is an age-related cartilage degenerative disease, and chondrocyte
senescence has been extensively studied in recent years. Increased numbers of senescent …

This review analyzes the relationship between microvesicles and reactive oxygen species
(ROS). This relationship is bidirectional; on the one hand, the number and content of …

Many countries are facing the aging of their population, and many more will face a similar
obstacle in the near future, which could be a burden to many healthcare systems. Increased …

Reactive oxygen species (ROS) affect many cellular functions and the proper redox balance
between ROS and antioxidants contributes substantially to the physiological welfare of the …

Premature ovarian insufficiency (POI) is clinically irreversible in women aged over 40 years.
Although numerous studies have demonstrated satisfactory outcomes of mesenchymal stem …

Survival and stemness of bone marrow mesenchymal stem cells (BMSCs) in osteonecrotic
areas are especially important in the treatment of early steroid-induced osteonecrosis of the …

A progressive loss of cartilage matrix leads to the development of osteoarthritis (OA). Matrix
homeostasis is disturbed in OA cartilage as the result of reduced production of cartilage …

Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …