Emerging technologies for molecular diagnosis of sepsis

M Sinha, J Jupe, H Mack, TP Coleman… - Clinical microbiology …, 2018 - Am Soc Microbiol
Rapid and accurate profiling of infection-causing pathogens remains a significant challenge
in modern health care. Despite advances in molecular diagnostic techniques, blood culture …

Defining neonatal sepsis

JL Wynn - Current opinion in pediatrics, 2016 - journals.lww.com
Defining neonatal sepsis : Current Opinion in Pediatrics Defining neonatal sepsis : Current
Opinion in Pediatrics Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …

Diagnostics for neonatal sepsis: current approaches and future directions

PY Iroh Tam, CM Bendel - Pediatric research, 2017 - nature.com
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Machine learning models for early sepsis recognition in the neonatal intensive care unit using readily available electronic health record data

AJ Masino, MC Harris, D Forsyth, S Ostapenko… - PloS one, 2019 - journals.plos.org
Background Rapid antibiotic administration is known to improve sepsis outcomes, however
early diagnosis remains challenging due to complex presentation. Our objective was to …

Neonatal bacterial sepsis

T Strunk, EJ Molloy, A Mishra, ZA Bhutta - The Lancet, 2024 - thelancet.com
Neonatal sepsis remains one of the key challenges of neonatal medicine, and together with
preterm birth, causes almost 50% of all deaths globally for children younger than 5 years …

Current research on the epidemiology, pathogenesis, and management of necrotizing enterocolitis

S Eaton, CM Rees, NJ Hall - Neonatology, 2017 - karger.com
Despite decades of research on necrotizing enterocolitis, we still do not fully understand the
pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of …

Neonatal sepsis prediction through clinical decision support algorithms: a systematic review

E Persad, K Jost, A Honoré, D Forsberg… - Acta …, 2021 - Wiley Online Library
Aim To systematically summarise the current evidence of employing clinical decision
support algorithms (CDSAs) using non‐invasive parameters for sepsis prediction in …

MicroRNA as an early biomarker of neonatal sepsis

M Jouza, J Bohosova, A Stanikova, J Pecl… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a major cause of lethality in neonatal intensive care units. Despite significant
advances in neonatal care and growing scientific knowledge about the disease, 4 of every …

New diagnostic possibilities for neonatal sepsis

C Tzialla, P Manzoni, C Achille, L Bollani… - American journal of …, 2018 - thieme-connect.com
Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS).
Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and …

Heart rate variability as a marker and predictor of inflammation, nosocomial infection, and sepsis–A systematic review

J Adam, S Rupprecht, ECS Künstler, D Hoyer - Autonomic Neuroscience, 2023 - Elsevier
Purpose The autonomic nervous system interacts with the immune system via the
inflammatory response. Heart rate variability (HRV), a marker of autonomic activity, is …