Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …

Proteins are involved in many biological processes. Misfolded, truncated, or mutated
proteins as well as over-or underexpressed proteins have been implicated in many …

Biological assay has been based on analysis of all individuals collected from sample
populations. Bulked sample analysis (BSA), which works with selected and pooled …

In the past few years, protein biochips have emerged as promising proteomic and diagnostic
tools for obtaining information about protein functions and interactions. Important …

Deciphering the cellular and molecular interactions that drive disease within the tissue
microenvironment holds promise for discovering drug targets of the future. In order to …

The emergence of systems biology is bringing forth a new set of challenges for advancing
science and technology. Defining ways of studying biological systems on a global level …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase of the ErbB family
that is abnormally activated in many epithelial tumors. Several mechanisms lead to the …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase of the ErbB
receptor family that is abnormally activated in many epithelial tumors. The aberrant …

Nanotechnology-based platforms for the high-throughput, multiplexed detection of proteins
and nucleic acids in heretofore unattainable abundance ranges promise to bring substantial …

Protein chips are widely used for high-throughput proteomic analysis, but to date, the low
sensitivity and narrow dynamic range have limited their capabilities in diagnostics and …