Current status of the diagnosis and management of osteoporosis

A Aibar-Almazán, A Voltes-Martínez… - International journal of …, 2022 - mdpi.com
Osteoporosis has been defined as the silent disease of the 21st century, becoming a public
health risk due to its severity, chronicity and progression and affecting mainly …

Update on osteoporosis screening and management

AK Anam, K Insogna - Medical Clinics, 2021 - medical.theclinics.com
Osteoporosis is a metabolic bone disease characterized by low bone mass and
microarchitectural deterioration of the bone tissue, leading to reduced bone strength and …

A systematic review and meta-analysis of bone loss in space travelers

M Stavnichuk, N Mikolajewicz, T Corlett, M Morris… - npj …, 2020 - nature.com
Bone loss in space travelers is a major challenge for long-duration space exploration. To
quantify microgravity-induced bone loss in humans, we performed a meta-analysis of …

Cytokine-scavenging nanodecoys reconstruct osteoclast/osteoblast balance toward the treatment of postmenopausal osteoporosis

Y Zhou, Y Deng, Z Liu, M Yin, M Hou, Z Zhao… - Science …, 2021 - science.org
Imbalance between osteoblasts and osteoclasts accounts for the incidence and
deterioration of postmenopausal osteoporosis. Abnormally elevated RANKL and TNF-α …

Exercise-linked skeletal irisin ameliorates diabetes-associated osteoporosis by inhibiting the oxidative damage–dependent miR-150-FNDC5/pyroptosis axis

J Behera, J Ison, MJ Voor, N Tyagi - Diabetes, 2022 - Am Diabetes Assoc
Recent evidence suggests that physical exercise (EX) promotes skeletal development.
However, the impact of EX on the progression of bone loss and deterioration of mechanical …

Bone turnover: Biology and assessment tools

P Szulc - Best practice & research Clinical endocrinology & …, 2018 - Elsevier
Bone turnover includes two processes: resorption (removal of old bone) and formation
(laying down of new bone). N-terminal propeptide of type I procollagen (PINP) and C …

Osteoporosis: molecular pathology, diagnostics, and therapeutics

B Adejuyigbe, J Kallini, D Chiou, JR Kallini - International journal of …, 2023 - mdpi.com
Osteoporosis is a major public health concern affecting millions of people worldwide and
resulting in significant economic costs. The condition is characterized by changes in bone …

A mini review on osteoporosis: from biology to pharmacological management of bone loss

KY Chin, BN Ng, MKI Rostam… - Journal of Clinical …, 2022 - mdpi.com
Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass
and microarchitecture, which compromises bone strength. It is a complex multifactorial …

Biomarkers as therapy monitoring for postmenopausal osteoporosis: a systematic review

F Migliorini, N Maffulli, F Spiezia, M Tingart… - Journal of Orthopaedic …, 2021 - Springer
Background Biochemical markers of bone turnover (BTMs), such as bone alkaline
phosphatase (bALP), procollagen type IN propeptide (PINP), serum cross-linked C …

Potential of biomarkers during pharmacological therapy setting for postmenopausal osteoporosis: a systematic review

F Migliorini, N Maffulli, F Spiezia, GM Peretti… - Journal of Orthopaedic …, 2021 - Springer
Background Biochemical markers of bone turnover (BTMs), such as the bone alkaline
phosphatase (bALP), procollagen type IN propeptide (PINP), serum cross-linked C …