The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Head and neck squamous cell carcinoma: update on epidemiology, diagnosis, and treatment

S Marur, AA Forastiere - Mayo Clinic Proceedings, 2016 - Elsevier
Squamous cell carcinoma arises from multiple anatomic subsites in the head and neck
region. The risk factors for development of cancers of the oral cavity, oropharynx …

NCCN Guidelines® insights: Head and neck cancers, version 1.2022: Featured updates to the NCCN guidelines

JJ Caudell, ML Gillison, E Maghami, S Spencer… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …

Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and …

JP Machiels, CR Leemans, W Golusinski… - Annals of …, 2020 - annalsofoncology.org
Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled …

H Mehanna, M Robinson, A Hartley, A Kong, B Foran… - The Lancet, 2019 - thelancet.com
Background The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer,
a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal growth …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for …

B O'Sullivan, SH Huang, J Su, AS Garden… - The Lancet …, 2016 - thelancet.com
Background Human papillomavirus-related (HPV+) oropharyngeal cancer is a rapidly
emerging disease with generally good prognosis. Many prognostic algorithms for …

[HTML][HTML] Human papillomavirus-related oropharyngeal cancer

M Taberna, M Mena, MA Pavón, L Alemany… - Annals of …, 2017 - Elsevier
High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …

E1308: phase II trial of induction chemotherapy followed by reduced-dose radiation and weekly cetuximab in patients with HPV-associated resectable squamous cell …

S Marur, S Li, AJ Cmelak, ML Gillison… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma
(OPSCC) is treatment-responsive. Definitive chemoradiation results in high cure rates but …

Rapid clearance profile of plasma circulating tumor HPV type 16 DNA during chemoradiotherapy correlates with disease control in HPV-associated oropharyngeal …

BS Chera, S Kumar, BT Beaty, D Marron, S Jefferys… - Clinical Cancer …, 2019 - AACR
Purpose: To identify a profile of circulating tumor human papilloma virus (HPV) DNA
(ctHPVDNA) clearance kinetics that is associated with disease control after …