Severe unconjugated hyperbilirubinemia, seen mainly in neonates, may cause kernicterus
and death. Conventional treatment for severe unconjugated hyperbilirubinemia consists of …

Background: Hyperbilirubinemia is a common neonatal problem. The present study aimed to
investigate the effect of ursodeoxycholic acid in reducing indirect hyperbilirubinemia of …

Introduction: Jaundice is one of the most common problems during infancy. It is believed that
breast milk jaundice is one of the reasons for the persistence of jaundice after 14 days of …

Background There are many pathological conditions leading to an elevated unconjugated
bilirubin level (hyperbilirubinaemia) in neonates. Currently the standard therapies for …

Background. Icterus tends to be one of the most prevalent causes of neonatal
hospitalization. The present study aimed to evaluate the effects of the different doses of …

Background: Neonatal jaundice is a prevalent disease that causes many complications,
including kernicterus and even death. Previous studies have shown that clofibrate as an …

Objective This study was designed to determine the effect of clofibrate on neonatal
uncomplicated jaundice treated with home phototherapy. Methods This clinical trial study …

Objective To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in
neonates. Methods A systematic review with meta-analysis of randomized controlled trials or …

Objective To evaluate the effect of single oral dose of 50 mg/kg clofibrate in
hyperbilirubinemia of term healthy neonates in Yazd, Iran. Methods A parallel single-blinded …

The aim of treating hyperbilirubinemia is preventing the serum bilirubin to reach neurotoxic
levels, which is done by phototherapy or blood transfusion. However, pharmacological …