Blood biomarkers for traumatic brain injury: a quantitative assessment of diagnostic and prognostic accuracy

ZS Gan, SC Stein, R Swanson, S Guan… - Frontiers in …, 2019 - frontiersin.org
Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …

Fatty acid-binding proteins as plasma markers of tissue injury

MMAL Pelsers, WT Hermens, JFC Glatz - Clinica chimica acta, 2005 - Elsevier
BACKGROUND: One of the novel and promising plasma markers for detection of tissue
injury is the family of 15 kDa cytoplasmic fatty acid-binding proteins of which various tissue …

The fatty acid transport function of fatty acid-binding proteins

J Storch, AEA Thumser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …

Tissue-specific functions in the fatty acid-binding protein family

J Storch, AE Thumser - Journal of Biological Chemistry, 2010 - ASBMB
The intracellular fatty acid-binding proteins (FABPs) are abundantly expressed in almost all
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …

Cellular fatty acid-binding proteins: their function and physiological significance

JFC Glatz, GJ van der Vusse - Progress in lipid research, 1996 - Elsevier
The various and dynamic functions fulfilled by long-chain fatty acids in mammals require that
sufficient amounts of these compounds are transported between tissues and within tissue …

The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function

AV Hertzel, DA Bernlohr - Trends in Endocrinology & Metabolism, 2000 - cell.com
Intracellular fatty acid-binding proteins associate with fatty acids and other hydrophobic
biomolecules in an internal cavity, providing for solubilization and metabolic trafficking …

Docosahexaenoic acid, fatty acid–interacting proteins, and neuronal function: breastmilk and fish are good for you

JR Marszalek, HF Lodish - Annu. Rev. Cell Dev. Biol., 2005 - annualreviews.org
In contrast to other tissues, the nervous system is enriched in the polyunsaturated fatty acids
(PUFAs): arachidonic acid (AA, 20: 4 n-6) and docosahexaenoic acid (DHA, 22: 6 n-3) …

Neurovascular unit as a source of ischemic stroke biomarkers—limitations of experimental studies and perspectives for clinical application

A Steliga, P Kowiański, E Czuba, M Waśkow… - Translational stroke …, 2020 - Springer
Cerebral stroke, which is one of the most frequent causes of mortality and leading cause of
disability in developed countries, often leads to devastating and irreversible brain damage …

Intracellular lipid-binding proteins and their genes

DA Bernlohr, MA Simpson, AV Hertzel… - Annual review of …, 1997 - annualreviews.org
▪ Abstract Intracellular lipid-binding proteins are a family of low-molecular-weight single-
chain polypeptides that form 1: 1 complexes with fatty acids, retinoids, or other hydrophobic …

Schizophrenia: the illness that made us human

DF Horrobin - Medical hypotheses, 1998 - Elsevier
Any hypotheses concerning the origins of humans must explain many things. Among these
are: 1, the growth in brain size around two million years ago; 2, the presence of …