Understanding vancomycin nephrotoxicity augmented by β-lactams: a synthesis of endosymbiosis, proximal renal tubule mitochondrial metabolism, and β-lactam …
S Alosaimy, MJ Rybak, G Sakoulas - The Lancet Infectious Diseases, 2023 - thelancet.com
The recent understanding that hydrophobic β-lactams have greater affinity for organic anion
transporter-3 (OAT-3) of the proximal renal tubule could provide valuable insights for …
transporter-3 (OAT-3) of the proximal renal tubule could provide valuable insights for …
The safety of ceftolozane/tazobactam for the treatment of complicated urinary tract infections
M Bassetti, A Vena, DR Giacobbe - Expert Opinion on Drug Safety, 2023 - Taylor & Francis
Introduction Ceftolozane is a cephalosporin similar to ceftazidime in its structure, which is
marketed in combination with tazobactam, a well-known β-lactamase inhibitor. Areas …
marketed in combination with tazobactam, a well-known β-lactamase inhibitor. Areas …
The Verdict on Vancomycin and Piperacillin/Tazobactam-Associated Nephrotoxicity: Acquittal by Biomarkers or Guilty as Charged?
S Lee, E Heil - Current Infectious Disease Reports, 2024 - Springer
Abstract Purpose of Review Current literature largely suggests that the combination of
vancomycin and piperacillin/tazobactam (VPT) is associated with a significantly higher risk …
vancomycin and piperacillin/tazobactam (VPT) is associated with a significantly higher risk …
Evaluation of Strategies for Reducing Vancomycin-Piperacillin/Tazobactam Incompatibility
A Martin Mena, L Négrier, A Treizebré, M Guilbert… - Pharmaceutics, 2023 - mdpi.com
Background: Drug incompatibility is defined as a physical-chemical reaction between two or
more injectable drugs and that results mainly in precipitation or insolubility. Several …
more injectable drugs and that results mainly in precipitation or insolubility. Several …
Comparative renal risk of long-term use of beta-lactams in combination with vancomycin across the continuum of care
LM Dolly, CG Rivera, KL Jensen… - Therapeutic …, 2023 - journals.sagepub.com
Background: Data are controversial regarding nephrotoxicity risk with vancomycin plus
piperacillin–tazobactam (VPT) compared to vancomycin alone or in combination with other …
piperacillin–tazobactam (VPT) compared to vancomycin alone or in combination with other …
Nephrotoxin Stewardship Alongside Antimicrobial Stewardship
MH Scheetz, J Chang, EF Barreto… - Clinical Infectious …, 2023 - academic.oup.com
TO THE EDITOR—We read with interest the article entitled“Nephrotoxicity of vancomycin in
combination with betalactam agents: ceftolozane-tazobactam vs. piperacillin-tazobactam”[1] …
combination with betalactam agents: ceftolozane-tazobactam vs. piperacillin-tazobactam”[1] …
Conception et évaluation de plusieurs stratégies permettant d'administrer simultanément des médicaments injectables incompatibles entre eux
L Négrier - 2023 - theses.hal.science
Le sujet du Doctorat d'Université a porté sur l'évaluation des modalités d'administration des
médicaments injectables impliquant un risque d'incompatibilité physico-chimique en …
médicaments injectables impliquant un risque d'incompatibilité physico-chimique en …