Human neutrophils: their role in cancer and relation to myeloid-derived suppressor cells

K Moses, S Brandau - Seminars in immunology, 2016 - Elsevier
Increased frequencies of peripheral blood neutrophils as well as tumor-infiltrating
(associated) neutrophils (TAN) have been observed in many tumor entities. Although the …

The V-ATPases in cancer and cell death

F Chen, R Kang, J Liu, D Tang - Cancer gene therapy, 2022 - nature.com
Transmembrane ATPases are membrane-bound enzyme complexes and ion transporters
that can be divided into F-, V-, and A-ATPases according to their structure. The V-ATPases …

Extracellular vesicles from mesenchymal stem cells activates VEGF receptors and accelerates recovery of hindlimb ischemia

P Gangadaran, RL Rajendran, HW Lee… - Journal of Controlled …, 2017 - Elsevier
Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) are potential
therapies for various diseases, but their angiogenic mechanisms of therapeutic efficacy …

The good, the bad, and the ugly: neutrophils, angiogenesis, and cancer

I Ozel, I Duerig, M Domnich, S Lang, E Pylaeva… - Cancers, 2022 - mdpi.com
Simple Summary Tumor angiogenesis is one of the most critical steps in the progression of
cancer. Owing to its fundamental role in tumor growth and metastasis, tumor angiogenesis is …

Tumor-associated neutrophils as new players in immunosuppressive process of the tumor microenvironment in breast cancer

F Hajizadeh, LA Maleki, M Alexander, MV Mikhailova… - Life sciences, 2021 - Elsevier
Despite the conventional reputation of neutrophils to have antibacterial properties, recent
studies have put emphasis and are interested in the role of neutrophils in the spread and …

The neutrophil lymphocyte ratio is associated with breast cancer prognosis: an updated systematic review and meta-analysis

B Wei, M Yao, C Xing, W Wang, J Yao… - OncoTargets and …, 2016 - Taylor & Francis
Breast cancer (BC) is the most common female malignancy within the spectrum of human
cancer. One promising way to reduce the mortality and morbidity of BC is to explore novel …

Neutrophils in cancer development and progression: roles, mechanisms, and implications

X Zhang, W Zhang, X Yuan, M Fu… - … journal of oncology, 2016 - spandidos-publications.com
Neutrophils are predominant immune cells that protect the host from microbial infection. The
roles of neutrophils in tumor have long been ignored due to their short life span and terminal …

Preoperative elevated neutrophil-to-lymphocyte ratio (NLR) and derived NLR are associated with poor prognosis in patients with breast cancer: a meta-analysis

J Duan, L Pan, M Yang - Medicine, 2018 - journals.lww.com
Background: Preoperative neutrophil-lymphocyte ratio (NLR) and derived NLR (dNLR) have
been suggested to be correlated with the prognosis of patients with breast cancer (BC) …

Cancer: fundamentals behind pH targeting and the double-edged approach

T Koltai - OncoTargets and therapy, 2016 - Taylor & Francis
The highly regulated pH of cells and the less-regulated pH of the surrounding extracellular
matrix (ECM) is the result of a delicate balance between metabolic processes and proton …

Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …