HMGB1 as a therapeutic target in disease
J Xue, JS Suarez, M Minaai, S Li… - Journal of cellular …, 2021 - Wiley Online Library
High‐mobility group box 1 (HMGB1) was initially recognized as a ubiquitous nuclear protein
involved in maintaining the nucleosome integrity and facilitating gene transcription. HMGB1 …
involved in maintaining the nucleosome integrity and facilitating gene transcription. HMGB1 …
MiRNA-mediated EMT and CSCs in cancer chemoresistance
B Dong, S Li, S Zhu, M Yi, S Luo, K Wu - Experimental Hematology & …, 2021 - Springer
Cancer stem cells (CSCs) are a small group of cancer cells, which contribute to
tumorigenesis and cancer progression. Cancer cells undergoing epithelial-to-mesenchymal …
tumorigenesis and cancer progression. Cancer cells undergoing epithelial-to-mesenchymal …
Silenced lncRNA H19 and up-regulated microRNA-129 accelerates viability and restrains apoptosis of PC12 cells induced by Aβ25-35 in a cellular model of …
YY Zhang, HL Bao, LX Dong, Y Liu, GW Zhang, FM An - Cell Cycle, 2021 - Taylor & Francis
Accumulating data manifest that long non-coding RNA (lncRNAs) are involved in all kinds of
neurodegenerative disorders, consisting of the onset and progression of Alzheimer's …
neurodegenerative disorders, consisting of the onset and progression of Alzheimer's …
MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway
G Wan, Y An, J Tao, Y Wang, Q Zhou, R Yang… - Bioscience …, 2020 - portlandpress.com
Secondary injury after spinal cord injury (SCI) is one reversible pathological change mainly
involving excessive inflammatory response and neuro-apoptosis. Since in recent years …
involving excessive inflammatory response and neuro-apoptosis. Since in recent years …
Multifunctional mesoporous silica-cerium oxide nanozymes facilitate miR129 delivery for high-quality healing of radiation-induced skin injury
D Zhou, M Du, H Luo, F Ran, X Zhao, Y Dong… - Journal of …, 2022 - Springer
Radiation-induced skin injury (RISI) is an important challenge for clinical treatments. The
main causes of RISI include hypoxia in the wound microenvironment, reactive oxygen …
main causes of RISI include hypoxia in the wound microenvironment, reactive oxygen …
LncRNA HOTAIR promotes breast cancer progression through regulating the miR-129-5p/FZD7 axis
D Wu, J Zhu, Y Fu, C Li, B Wu - Cancer Biomarkers, 2021 - content.iospress.com
Breast cancer is the most common malignancies worldwide. LncRNA HOX transcript
antisense intergenic RNA (HOTAIR) has been shown to promote progression and …
antisense intergenic RNA (HOTAIR) has been shown to promote progression and …
Emodin alleviates sepsis‐mediated lung injury via inhibition and reduction of NF‐kB and HMGB1 pathways mediated by SIRT1
FJ Liu, TJ Gu, DY Wei - The Kaohsiung Journal of Medical …, 2022 - Wiley Online Library
Inflammation plays an important role during sepsis, and excessive inflammation can result in
organ damage, chronic inflammation, fibrosis, and scarring. The study aimed to investigate …
organ damage, chronic inflammation, fibrosis, and scarring. The study aimed to investigate …
Damage-associated molecular patterns modulation by microRNA: relevance on immunogenic cell death and cancer treatment outcome
MJ Lamberti, A Nigro, V Casolaro, NB Rumie Vittar… - Cancers, 2021 - mdpi.com
Simple Summary Inside the cell, damage-associated molecular pattern molecules (DAMPs)
play several physiological functions, but when they are released or translocated to the …
play several physiological functions, but when they are released or translocated to the …
[HTML][HTML] LncRNA HOTAIR suppresses cell apoptosis, autophagy and induces cell proliferation in cholangiocarcinoma by modulating the miR-204-5p/HMGB1 axis
M Lu, X Qin, Y Zhou, G Li, Z Liu, H Yue… - Biomedicine & …, 2020 - Elsevier
Background Cholangiocarcinoma (CCA) is a malignant tumor in the world. LncRNA HOX
transcript antisense intergenic RNA (HOTAIR) was identified as a crucial regulator in various …
transcript antisense intergenic RNA (HOTAIR) was identified as a crucial regulator in various …
Gastric cancer cell-derived extracellular vesicles elevate E2F7 expression and activate the MAPK/ERK signaling to promote peritoneal metastasis through the delivery …
F Zhang, C Guo, X Cao, Y Yan, J Zhang, S Lv - Cell death discovery, 2022 - nature.com
Cancer cell-derived extracellular vesicles (EVs) have extensive application in the formation
of their environment, including metastasis. This study explored the ability of gastric cancer …
of their environment, including metastasis. This study explored the ability of gastric cancer …