Rate thresholds in cell signaling have functional and phenotypic consequences in non-linear time-dependent environments

A Thiemicke, G Neuert - Frontiers in cell and developmental biology, 2023 - frontiersin.org
All cells employ signal transduction pathways to respond to physiologically relevant
extracellular cytokines, stressors, nutrient levels, hormones, morphogens, and other stimuli …

Phenotypic consequences of logarithmic signaling in MAPK stress response

H Jashnsaz, G Neuert - iScience, 2025 - cell.com
How cells respond to dynamic environmental changes is crucial for understanding
fundamental biological processes and cell physiology. In this study, we developed an …

Measuring regulatory network inheritance in dividing yeast cells using ordinary differential equations

W Wu, T Kennedy, O Arguello-Miranda, KZ Lin - bioRxiv, 2024 - biorxiv.org
Quantifying the inheritance of regulatory networks among proteins during asymmetric cell
division remains a challenge due to the complexity of these systems and the lack of robust …

Dynamic transcoding properties of NF-κB signaling

CS Mokashi - 2022 - search.proquest.com
All biological systems constantly receive, process and respond to external signals. Cells,
although being the basic unit of life, show remarkable ability to decipher the environmental …