Benzylic stereogenic centers are ubiquitous in natural products and pharmaceuticals. A
potentially general, though challenging, approach toward their selective creation would be …

The development of visible-light-induced photoacid catalyzed glycosylation is reported. The
eosin Y and PhSSPh catalyst system is applied to realize glycosylation with different …

Polyunsaturated fatty acids and their metabolites have been reported in which their pathway
has potential for the modulation of cancer cell growth. 13-(S)-HODE and 15-(S)-HETE, both …

Spatial control of reactivity is intrinsically difficult in gold catalysis due to the linear
coordination mode of Au (I) and the commonly flat ligands employed for Au (III) complexes …

Trichloroacetimidates are commonly synthesized to be used as alkylating or glycosylating
reagents. They are synthesized from an alcohol and trichloroacetonitrile and DBU is the …

Herein, we describe a simple and efficient pathway for the total synthesis of pyranicin and 4‐
epi‐pyranicin by utilizing carbohydrates as chiral raw materials for the first time. The general …

The first total syntheses of seiricuprolide and pestalotioprolide B, rare 14‐membered α, β‐
unsaturated macrolides embedding a chiral epoxide motif, were achieved in 17 steps with …

Lost in post‐translation. Cordycicadins A–D are four C20 polyketides, all containing ag‐
lactone fused to a 10‐membered lactone. The proposed biosynthetic pathway for the …

Reactions that proceed via carbocations play a big role in various chemical transformations
for over a century. Their applications range from drug discovery, commercial compounds to …

Salvinorin A ist ein psychotroper Naturstoff, welcher 1982 erstmals aus den getrockneten
Blättern des Azteken-Salbeis (Salvia divinorum) extrahiert wurde. Er besitzt eine geringe …