Plant antimicrobial peptides

R Nawrot, J Barylski, G Nowicki, J Broniarczyk… - Folia microbiologica, 2014 - Springer
Plant antimicrobial peptides (AMPs) are a component of barrier defense system of plants.
They have been isolated from roots, seeds, flowers, stems, and leaves of a wide variety of …

The evolution, function and mechanisms of action for plant defensins

K Parisi, TMA Shafee, P Quimbar… - Seminars in cell & …, 2019 - Elsevier
Plant defensins are an extensive family of small cysteine rich proteins characterised by a
conserved cysteine stabilised alpha beta protein fold which resembles the structure of insect …

Properties and mechanisms of action of naturally occurring antifungal peptides

NL Van der Weerden, MR Bleackley… - Cellular and molecular …, 2013 - Springer
Antimicrobial peptides are a vital component of the innate immune system of all eukaryotic
organisms and many of these peptides have potent antifungal activity. They have potential …

Antifungal plant defensins: mechanisms of action and production

K Vriens, BPA Cammue, K Thevissen - Molecules, 2014 - mdpi.com
Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …

Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Antifungal peptides: To be or not to be membrane active

M Rautenbach, AM Troskie, JA Vosloo - Biochimie, 2016 - Elsevier
Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have
alternative targets. Fungal membranes share many characteristics with mammalian …

Antimicrobial Peptides with Anti-Candida Activity

A Perez-Rodriguez, E Eraso, G Quindós… - International journal of …, 2022 - mdpi.com
Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …

Plant defensins: common fold, multiple functions

NL Van der Weerden, MA Anderson - Fungal Biology Reviews, 2013 - Elsevier
Plant defensins represent a large class of structurally similar peptides found throughout the
plant kingdom. Despite a conserved cysteine spacing pattern and three-dimensional …

Identification of a new class of antifungals targeting the synthesis of fungal sphingolipids

V Mor, A Rella, AM Farnoud, A Singh, M Munshi… - MBio, 2015 - Am Soc Microbiol
Recent estimates suggest that> 300 million people are afflicted by serious fungal infections
worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of …

Defensins: antifungal lessons from eukaryotes

PM Silva, S Gonçalves, NC Santos - Frontiers in microbiology, 2014 - frontiersin.org
Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research
toward the finding of a viable alternative to current antifungal drugs. Defensins are one of the …