Hybrid small-molecule/protein fluorescent probes

M Minoshima, SI Reja, R Hashimoto, K Iijima… - Chemical …, 2024 - ACS Publications
Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Organic dye based nanoparticles for cancer phototheranostics

Y Cai, W Si, W Huang, P Chen, J Shao, X Dong - Small, 2018 - Wiley Online Library
Phototheranostics, which simultaneously combines photodynamic and/or photothermal
therapy with deep‐tissue diagnostic imaging, is a promising strategy for the diagnosis and …

Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue

W Chen, J Dong, L Plate, DE Mortenson… - Journal of the …, 2016 - ACS Publications
Arylfluorosulfates have appeared only rarely in the literature and have not been explored as
probes for covalent conjugation to proteins, possibly because they were assumed to …

Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo

MA Plamont, E Billon-Denis, S Maurin… - Proceedings of the …, 2016 - National Acad Sciences
This paper presents Yellow Fluorescence-Activating and absorption-Shifting Tag (Y-FAST),
a small monomeric protein tag, half as large as the green fluorescent protein, enabling …

Cyanine polyene reactivity: scope and biomedical applications

AP Gorka, RR Nani, MJ Schnermann - Organic & biomolecular …, 2015 - pubs.rsc.org
Cyanines are indispensable fluorophores that form the chemical basis of many fluorescence-
based applications. A feature that distinguishes cyanines from other common fluorophores is …

Fluorogenic labeling strategies for biological imaging

C Li, AG Tebo, A Gautier - International Journal of Molecular Sciences, 2017 - mdpi.com
The spatiotemporal fluorescence imaging of biological processes requires effective tools to
label intracellular biomolecules in living systems. This review presents a brief overview of …

A plant lipocalin promotes retinal-mediated oscillatory lateral root initiation

AJ Dickinson, J Zhang, M Luciano, G Wachsman… - Science, 2021 - science.org
In Arabidopsis, de novo organogenesis of lateral roots is patterned by an oscillatory
mechanism called the root clock, which is dependent on unidentified metabolites. To …

Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters

D Zhang, Z Chen, Z Du, B Bao, N Su, X Chen, Y Ge… - Cell Discovery, 2023 - nature.com
Naturally occurring fluorescent proteins (FPs) are the most widely used tools for tracking
cellular proteins and sensing cellular events. Here, we chemically evolved the self-labeling …

Design of large stokes shift fluorescent proteins based on excited state proton transfer of an engineered photobase

EM Santos, W Sheng… - Journal of the …, 2021 - ACS Publications
The incredible potential for fluorescent proteins to revolutionize biology has inspired the
development of a variety of design strategies to address an equally broad range of …

Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

J Kwon, JS Park, M Kang, S Choi, J Park… - Nature …, 2020 - nature.com
We introduce UnaG as a green-to-dark photoswitching fluorescent protein capable of high-
quality super-resolution imaging with photon numbers equivalent to the brightest …