The progression of many neurodegenerative diseases is thought to be driven by the
template-directed misfolding, seeded aggregation and cell–cell transmission of …

The development of α‐synuclein immunoreactive aggregates in selectively vulnerable
neuronal types of the human central, peripheral, and enteric nervous systems is crucial for …

Sporadic Parkinson's disease involves multiple neuronal systems and results from changes
developing in a few susceptible types of nerve cells. Essential for neuropathological …

The synucleinopathy, idiopathic Parkinson's disease, is a multisystem disorder that involves
only a few predisposed nerve cell types in specific regions of the human nervous system …

There has been an explosion in the number of papers discussing the hypothesis
of'pathogenic spread'in neurodegenerative disease—the idea that abnormal forms of …

Accumulating evidence suggests that sporadic Parkinson's disease has a long prodromal
period during which several non‐motor features develop, in particular, impairment of …

The substantia nigra is not the induction site in the brain of the neurodegenerative process
underlying Parkinson disease (PD). Instead, the results of this semi-quantitative study of 30 …

In Parkinson's disease patients pathology follows a characteristic pattern involving inter alia
the enteric nervous system, the dorsal motor nucleus of the vagus, the intermediolateral …

The synucleinopathy known as sporadic Parkinson's disease (PD) is a multisystem disorder
that severely damages predisposed nerve cell types in circumscribed regions of the human …

Previous data on the prevalence of olfactory dysfunction in Parkinson´ s disease (PD) range
from 45% to 90%. The present multicenter study aimed to provide data on the prevalence of …