GABA tone regulation and its cognitive functions in the brain
Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
[HTML][HTML] Effects of oral gamma-aminobutyric acid (GABA) administration on stress and sleep in humans: A systematic review
P Hepsomali, JA Groeger, J Nishihira… - Frontiers in …, 2020 - frontiersin.org
Gamma-aminobutyric acid (GABA) is a non-proteinogenic amino acid and is the main
inhibitory neurotransmitter in the mammalian brain. GABA's stress-reducing, and sleep …
inhibitory neurotransmitter in the mammalian brain. GABA's stress-reducing, and sleep …
Neural circuitry of wakefulness and sleep
TE Scammell, E Arrigoni, JO Lipton - Neuron, 2017 - cell.com
Sleep remains one of the most mysterious yet ubiquitous animal behaviors. We review
current perspectives on the neural systems that regulate sleep/wake states in mammals and …
current perspectives on the neural systems that regulate sleep/wake states in mammals and …
Multiscale modeling meets machine learning: What can we learn?
GCY Peng, M Alber, A Buganza Tepole… - … Methods in Engineering, 2021 - Springer
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …
biological, biomedical, and behavioral sciences. There can be no argument that this …
Systems chronotherapeutics
Chronotherapeutics aim at treating illnesses according to the endogenous biologic rhythms,
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …
Regulating the suprachiasmatic nucleus (SCN) circadian clockwork: interplay between cell-autonomous and circuit-level mechanisms
ED Herzog, T Hermanstyne… - Cold Spring …, 2017 - cshperspectives.cshlp.org
The suprachiasmatic nucleus (SCN) is the principal circadian clock of the brain, directing
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
Recent advances in the utilization of tea active ingredients to regulate sleep through neuroendocrine pathway, immune system and intestinal microbiota
Y Wei, J Xu, S Miao, K Wei, L Peng… - Critical Reviews in …, 2023 - Taylor & Francis
Sleep disorders have received widespread attention nowadays, which have been promoted
by the accelerated pace of life, unhealthy diets and lack of exercise in modern society. The …
by the accelerated pace of life, unhealthy diets and lack of exercise in modern society. The …
Elevated CO2 impairs olfactory‐mediated neural and behavioral responses and gene expression in ocean‐phase coho salmon (Oncorhynchus kisutch)
CR Williams, AH Dittman, P McElhany… - Global change …, 2019 - Wiley Online Library
Elevated concentrations of CO2 in seawater can disrupt numerous sensory systems in
marine fish. This is of particular concern for Pacific salmon because they rely on olfaction …
marine fish. This is of particular concern for Pacific salmon because they rely on olfaction …
GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time
The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus
The hypothalamic suprachiasmatic nucleus (SCN) is the master mammalian circadian clock.
Its cell-autonomous timing mechanism, a transcriptional/translational feedback loop (TTFL) …
Its cell-autonomous timing mechanism, a transcriptional/translational feedback loop (TTFL) …