The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity
Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
Intricacies of TGF-β signaling in Treg and Th17 cell biology
Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …
central to the balance between immune tolerance and immune rejection. Th cells adopt …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
Treg heterogeneity, function, and homeostasis
D Shevyrev, V Tereshchenko - Frontiers in immunology, 2020 - frontiersin.org
T-regulatory cells (Tregs) represent a unique subpopulation of helper T-cells by maintaining
immune equilibrium using various mechanisms. The role of T-cell receptors (TCR) in …
immune equilibrium using various mechanisms. The role of T-cell receptors (TCR) in …
[HTML][HTML] Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective
Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …
A review on the design of hydrogels with different stiffness and their effects on tissue repair
T Luo, B Tan, L Zhu, Y Wang, J Liao - Frontiers in bioengineering and …, 2022 - frontiersin.org
Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …
medicine. Hydrogels have become one of the most important scaffolds for tissue …
[HTML][HTML] Immunomodulatory bioactive glasses for tissue regeneration
The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …
have been evidenced in the last decade. Immune cells play central roles in immune …
Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …
Interleukin-2 and regulatory T cells in rheumatic diseases
Failure of regulatory T (Treg) cells to properly control immune responses leads invariably to
autoimmunity and organ damage. Decreased numbers or impaired function of Treg cells …
autoimmunity and organ damage. Decreased numbers or impaired function of Treg cells …
Toward a better regeneration through implant‐mediated immunomodulation: harnessing the immune responses
Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …
physiological processes wherein immune responses play a crucial role to enable tissue …