Motor behavioral deficits in the cuprizone model: Validity of the rotarod test paradigm
C Lubrich, P Giesler, M Kipp - International journal of molecular sciences, 2022 - mdpi.com
Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …
characterized by multifocal inflammatory demyelinating lesions affecting both the central …
Behavioural phenotypes in the cuprizone model of central nervous system demyelination
The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …
processes of demyelination and remyelination, with many papers adopting a narrative linked …
Astrocytic neuroimmunological roles interacting with microglial cells in neurodegenerative diseases
M Gotoh, Y Miyamoto, H Ikeshima-Kataoka - International journal of …, 2023 - mdpi.com
Both astrocytic and microglial functions have been extensively investigated in healthy
subjects and neurodegenerative diseases. For astrocytes, not only various sub-types were …
subjects and neurodegenerative diseases. For astrocytes, not only various sub-types were …
Astrocyte ablation induced by La-aminoadipate (L-AAA) potentiates remyelination in a cuprizone demyelinating mouse model
Chronic demyelination in the central nervous system (CNS) is accompanied by an increase
in the number of reactive astrocytes and astrogliosis. There are controversial issues …
in the number of reactive astrocytes and astrogliosis. There are controversial issues …
Natural compounds as potential therapeutic candidates for multiple sclerosis: Emerging preclinical evidence
J Yuan, Y Tao, M Wang, F Huang, X Wu - Phytomedicine, 2024 - Elsevier
Background Multiple sclerosis is a chronic neurodegenerative disease, with main
characteristics of pathological inflammation, neural damage and axonal demyelination …
characteristics of pathological inflammation, neural damage and axonal demyelination …
Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease
S Yamamoto, K Yamashina, M Ishikawa… - Journal of …, 2017 - Springer
Background Multiple sclerosis is a neuroinflammatory demyelinating and
neurodegenerative disease of the central nervous system characterized by recurrent and …
neurodegenerative disease of the central nervous system characterized by recurrent and …
Sex differences in the behavioural aspects of the cuprizone-induced demyelination model in mice
Multiple sclerosis is an autoimmune disease characterised by demyelination in the central
nervous system. The cuprizone-induced demyelination model is often used in mice to test …
nervous system. The cuprizone-induced demyelination model is often used in mice to test …
The flavonoid Baicalein attenuates cuprizone-induced demyelination via suppression of neuroinflammation
M Hashimoto, S Yamamoto, K Iwasa, K Yamashina… - Brain research …, 2017 - Elsevier
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system
characterized by recurrent and progressive demyelination/remyelination cycles …
characterized by recurrent and progressive demyelination/remyelination cycles …
Protective features of calorie restriction on cuprizone-induced demyelination via modulating microglial phenotype
Multiple sclerosis (MS) is an immune-mediated demyelinating disorder in the central
nervous system (CNS) with no definitive treatment, but it can be alleviated by changing life …
nervous system (CNS) with no definitive treatment, but it can be alleviated by changing life …
Myricetin alleviates cuprizone-induced behavioral dysfunction and demyelination in mice by Nrf2 pathway
Multiple sclerosis (MS) is a demyelinating disease occurring in the central nervous system.
In the present study, we evaluated the function of myricetin on the alleviation of behavioral …
In the present study, we evaluated the function of myricetin on the alleviation of behavioral …