Long COVID science, research and policy

Z Al-Aly, H Davis, L McCorkell, L Soares… - Nature Medicine, 2024 - nature.com
Long COVID represents the constellation of post-acute and long-term health effects caused
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …

Long COVID: a clinical update

T Greenhalgh, M Sivan, A Perlowski, JŽ Nikolich - The Lancet, 2024 - thelancet.com
Summary Post-COVID-19 condition (also known as long COVID) is generally defined as
symptoms persisting for 3 months or more after acute COVID-19. Long COVID can affect …

The IUPHAR/BPS guide to PHARMACOLOGY in 2024

SD Harding, JF Armstrong, E Faccenda… - Nucleic acids …, 2024 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; https://www.
guidetopharmacology. org) is an open-access, expert-curated, online database that …

Long COVID: a review and proposed visualization of the complexity of long COVID

R Perumal, L Shunmugam, K Naidoo… - Frontiers in …, 2023 - frontiersin.org
Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2)
infection, or Long COVID, is a prevailing second pandemic with nearly 100 million affected …

[HTML][HTML] Mechanisms of long COVID and the path toward therapeutics

MJ Peluso, SG Deeks - Cell, 2024 - cell.com
Long COVID, a type of post-acute sequelae of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(PASC) defined by medically unexplained symptoms following …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection

SA Narayanan, DA Jamison Jr, JW Guarnieri… - European Journal of …, 2024 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and
mortality worldwide. The betacoronavirus continues to evolve with global health implications …

Understanding long COVID; mitochondrial health and adaptation—old pathways, new problems

AVW Nunn, GW Guy, W Brysch, JD Bell - Biomedicines, 2022 - mdpi.com
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as “brain fog”,
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …

Pathophysiological involvement of host mitochondria in SARS-CoV-2 infection that causes COVID-19: A comprehensive evidential insight

C Bhowal, S Ghosh, D Ghatak, R De - Molecular and cellular biochemistry, 2023 - Springer
SARS-CoV-2 is a positive-strand RNA virus that infects humans through the nasopharyngeal
and oral route causing COVID-19. Scientists left no stone unturned to explore a targetable …

sChemNET: a deep learning framework for predicting small molecules targeting microRNA function

D Galeano, Imrat, J Haltom, C Andolino… - Nature …, 2024 - nature.com
MicroRNAs (miRNAs) have been implicated in human disorders, from cancers to infectious
diseases. Targeting miRNAs or their target genes with small molecules offers opportunities …

Diabetes mellitus, energy metabolism, and COVID-19

C Conte, E Cipponeri, M Roden - Endocrine Reviews, 2024 - academic.oup.com
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …