Managing an older adult with cancer: considerations for radiation oncologists

S Chang, NE Goldstein… - BioMed Research …, 2017 - Wiley Online Library
Older adults with cancer present a unique set of management complexities for oncologists
and radiation oncologists. Prognosis and resilience to cancer treatments are notably …

Hypofractionated versus standard radiation therapy in combination with temozolomide for glioblastoma in the elderly: a meta-analysis

VM Lu, P Kerezoudis, DA Brown, TC Burns… - Journal of neuro …, 2019 - Springer
Background There is no clear consensus regarding the optimal treatment for glioblastoma
(GBM) in the elderly. Hypofractionated radiation therapy (hRT) has emerged as a viable and …

Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged≥ 75 …

M Ohno, Y Miyakita, M Takahashi, H Igaki… - Radiation …, 2019 - Springer
Background and purpose The purpose of this study was to evaluate the outcomes of elderly
patients (aged≥ 75 years) with newly diagnosed glioblastoma (GBM), who were treated …

β-Elemene Selectively Inhibits the Proliferation of Glioma Stem-Like Cells Through the Downregulation of Notch1

H Feng, J Wang, H Jiang, X Mei, Y Zhao… - Stem cells …, 2017 - academic.oup.com
Glioma is the most frequent primary central nervous system tumor. Although the current first-
line medicine, temozolomide (TMZ), promotes patient survival, drug resistance develops …

Optimal managements of elderly patients with glioblastoma

Y Arakawa, Y Mineharu, M Uto… - Japanese Journal of …, 2022 - academic.oup.com
Optimizing the management of elderly patients with glioblastoma is an ongoing task in neuro-
oncology. The number of patients with this tumor type is gradually increasing with the aging …

Comparative outcomes of short-term and long-term fractionation with temozolomide in older glioblastoma patients: Single-center experience

B Uysal, H Gamsiz, O Sager, F Dincoglan… - Journal of Cancer …, 2022 - journals.lww.com
Background: The main goal of our study is to comparatively evaluate outcomes of
hypofractionation and long-term fractionation with temozolomide (TMZ) in glioblastoma …

Radiotherapy in brain tumors

M Flores-Castro, G Sebastian-Barajas - … of Neuro-Oncology: Brain & Skull …, 2021 - Springer
The incidence of primary brain tumors treated with RT in adults is low in relation with other
tumors of the body, the most frequent tumors are gliomas, of adult gliomas, 80% are high …

Radiotherapy for Geriatric Cancer Patients: Five-year Experience at a North Indian Tertiary Care Hospital

G Trivedi, S Singh, N Lohia, S Harish… - Asian Pacific Journal of …, 2023 - waocp.com
Background: The incidence of malignancy in elderly population in India has risen due to
increased life expectancy, health awareness, and access to tertiary health care …

[PDF][PDF] Radioresistencia en glioblastoma: papel de la hipoxia en la genotoxicidad inducida por radiaciones ionizantes

KC Forero, MB Langer, AM Paternina… - … e Investigación Medico …, 2018 - academia.edu
Objetivo: El glioblastoma multiforme es el astrocitoma grado IV más frecuente en la edad
adulta, caracterizado una alta radioresistencia, que se asocia a la presencia de regiones …

[PDF][PDF] Radiotherapy for Geriatric Cancer Patients: Five-year Experience at a North Indian Tertiary Care Hospital

N Bisht, S Viswanath, M Prashar, G Tripathi - academia.edu
Background: The incidence of malignancy in elderly population in India has risen due to
increased life expectancy, health awareness, and access to tertiary health care …