A war on many fronts: cross disciplinary approaches for novel cancer treatment strategies

A Del Pino Herrera, MC Ferrall-Fairbanks - Frontiers in Genetics, 2024 - frontiersin.org
Cancer is a disease characterized by uncontrolled cellular growth where cancer cells take
advantage of surrounding cellular populations to obtain resources and promote invasion …

Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model

DR Bergman, Y Wang, E Trujillo, AA Fernald… - Frontiers in …, 2024 - frontiersin.org
Bladder cancer is an increasingly prevalent global disease that continues to cause morbidity
and mortality despite recent advances in treatment. Immune checkpoint inhibitors (ICI) and …

[HTML][HTML] Theoretical understanding of evolutionary dosing following tumor dynamics

MA Masud, E Kim - Chaos, Solitons & Fractals, 2024 - Elsevier
Recent preclinical and clinical studies have suggested that evolution-based cancer
therapies exploiting intratumor competition can significantly delay resistance. Various …

A calibration and uncertainty quantification analysis of classical, fractional and multiscale logistic models of tumour growth

NM Dimitriou, E Demirag, K Strati, GD Mitsis - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective: The validation of mathematical models of tumour growth
is frequently hampered by the lack of sufficient experimental data, resulting in qualitative …

Validation of polymorphic Gompertzian model of cancer through in vitro and in vivo data

A Soboleva, A Kaznatcheev, R Cavill, K Schneider… - bioRxiv, 2023 - biorxiv.org
Mathematical modeling plays an important role in our understanding and targeting therapy
resistance mechanisms in cancer. The polymorphic Gompertzian model, analyzed …

Advancing Tumor Control: The Promise of Adaptive Therapy

HI Richker - 2023 - search.proquest.com
This review aims to provide a comprehensive review of the most recent literature on
adaptive therapy, a promising new approach to cancer treatment that leverages evolutionary …