Susceptibility to psychiatric disorders seems to be influenced by environmental disturbances
throughout all stages of life. Epigenetics is described as a key “bridge” between gene and …

Epigenetic modifications regulate gene expression for development, immune response,
disease, and other processes. A major role of epigenetics is to control the dynamics of …

Background: Fetal alcohol spectrum disorders (FASD) represent a leading cause of non-
genetic neuropathologies. Recent preclinical evidence from suggests that prenatal ethanol …

Single-cell transcriptomic platforms provide an opportunity to map an organism's response
to environmental cues with high resolution. Here, we applied single-nucleus RNA …

Previously it has been shown that fetal alcohol exposure increases the stress response
partly due to lowering stress regulatory proopiomelanocortin (Pomc) gene expression in the …

Background Despite many advances in treatment, the prognosis of patients with sepsis still
remains poor. Polymorphonuclear leukocytes (PMNs) are the first line of defense against …

Background Recent research has indicated that parental use of central nervous system-
targeting medications during periconceptional periods may affect offspring across various …

Background Alcohol drinking during pregnancy often adversely affects brain development
among offspring, inducing persistent central nervous system dysfunction. However, it is …

As the most consumed drug in the world, alcohol is well-characterized for its toxicity. Ethanol
in alcoholic beverages can diffuse across cell membranes, the blood–brain barrier, and the …

Alcohol consumption during pregnancy harms fetal development, leading to various
physical and behavioral issues. This study investigates how prenatal ethanol exposure …