In recent years, a new target closely linked to a variety of diseases has appeared in the
researchers' vision, which is the NLRP3 inflammasome. With the deepening of the study of …

Introduction Sensorineural hearing impairment (SNHI), a common childhood disorder with
heterogeneous genetic causes, can lead to delayed language development and …

The efficacy of vitamin C in age-related hearing loss, ie, presbycusis, remains debatable. On
a separate note, inflammation induced by the NOD-like receptor family pyrin domain …

Objective Cryopyrin‐associated periodic syndromes (CAPS), also known as NLRP3‐
associated autoinflammatory diseases, are a spectrum of rare autoinflammatory diseases …

Sensorineural hearing loss (SNHL) is a common otologic condition caused by damage to
hair cells and spiral ganglion neurons that affects transmission pathways. Most of these cells …

The etiology of hearing impairment is multifactorial, with contributions from both genetic and
environmental factors. Although genetic studies have yielded valuable insights into the …

Tumor necrosis factor type 1A receptor‐associated periodic syndrome (TRAPS) and
cryopyrin‐associated autoinflammatory syndrome (CAPS) are rare monogenic …

Cryopyrin-associated periodic syndromes (CAPS) also known as NLRP3-associated auto-
inflammatory diseases, are a spectrum of rare auto-inflammatory diseases caused by gain-of …

Purpose: The aim of this study was to report a novel heterozygous variant c. 1712G> T (p.
Gly571Val) in the nucleotide-binding domain, leucine-rich repeat family, pyrin domain …

Vitamin C, a nutrient present in various food items, has been found to possess anti-
inflammatory and antioxidant properties. The efficacy of vitamin C in age-related hearing …