Considering the small number of papers assessing the conformational profile of
glycoproteins through molecular dynamics (MD) simulations, the current work reports on a …

Knowledge of the three-dimensional structures of the carbohydrate molecules is
indispensable for a full understanding of the molecular processes in which carbohydrates …

Glycoproteins are synthesized in most of the living organisms, being major components of
the outer surface of mammalian cells and most of the secreted proteins in eukaryotes …

Gaucher disease, an autosomal recessive disorder, is caused by a deficiency of
glucocerebrosidase (GCase) enzyme, a peripheral membrane-associated glycoprotein that …

A concise and novel method for site-selective alkylation of 1, 3, 6′, 3 ″-
tetraazidokanamycin has been developed that leads to the divergent synthesis of three …

The possibility of secondary structure acting as a primary determinant in nature's choice of
the consensus sequon, NXS/T in all N-linked glycoproteins, has been addressed by …

A novel and simple model was proposed to explain the different relative orientation of the
peptide backbone and presentation of beta-N-scetyl-D-glucosamine (β-O-GlcNAc)-Thr and …

N-Acylglucosamine is an important component in many oligosaccharides in eukaryotes,
where it plays a very important biological role. Located between a glucose ring and an alkyl …

N‐Glycoprotein linkage region constituents, 2‐acetamido‐2‐deoxy‐β‐d‐glucopyranose
(GlcNAc) and asparagine (Asn) are conserved among all the eukaryotes. To gain a better …

The biological addition of oligosaccharide moieties to asparagine residues of N-
glycoproteins influences the properties and bioactivities of these macromolecules. The low …